Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382303 | 0.82 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL5148188 | 0.80 | NOS1 (0.44) | ALDH1A1SMN1; SMN2GAAMAPTTSHR | |
| SCHEMBL27920273 | 0.74 | ALDH1A1 (0.44) | ALDH1A1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL27920275 | 0.71 | ALDH1A1 (0.38) | ALDH1A1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL7036611 | 0.67 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2GAAMAPT | |
| P-Xylene SCHEMBL10441943 | 0.67 | ALDH1A1 (0.55) | ALDH1A1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL6132418 | 0.67 | CA1 (0.49) | RAB9ASMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL10564707 | 0.67 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL11773014 | 0.67 | KIF11 (0.44) | ALDH1A1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL27935684 | 0.67 | RAB9A (0.39) | ALDH1A1RAB9ASMN1; SMN2GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831077-A | REACTING AN AQUEOUS HYDRAINE HYDRATE WITH A REDUCING SUGAR IN PRESENCE OF A BEASE | REDMOND JOHN WILLIAM (AU) | 1998-11-03 | — | — | US | disclosed |