Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598124 | 0.80 | MEN1 (0.72) | ALDH1A1MEN1KMT2ADNMT1CACNA1B | |
| SCHEMBL30066036 | 0.80 | MEN1 (0.72) | ALDH1A1MEN1KMT2ADNMT1CACNA1B | |
| SCHEMBL31035951 | 0.80 | MEN1 (0.72) | ALDH1A1MEN1KMT2ADNMT1CACNA1B | |
| Methane SCHEMBL7938130 | 0.78 | MEN1 (0.69) | ALDH1A1MEN1KMT2ADNMT1CACNA1B | |
| SCHEMBL1556427 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ADNMT1CACNA1B | |
| SCHEMBL27615312 | 0.77 | CYP1A2 (0.52) | ALDH1A1CYP1A2MAOAERBB2FYN | |
| SCHEMBL2779798 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACYP1A2MAOA | |
| Anthracene SCHEMBL28076700 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ADNMT1CACNA1B | |
| SCHEMBL7938127 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ADNMT1CACNA1B | |
| SCHEMBL28352156 | 0.74 | CYP1A2 (0.61) | ALDH1A1MEN1KMT2ADNMT1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027555-B1 | METHOD FOR EXFOLIATING GRAPHITE ASSISTED BY A DIELS-ALDER REACTION | UNIV BORDEAUX (FR) | 2023-05-24 | — | — | EP | disclosed |
| US-9849196-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| US-9718692-B2 | Method for exfoliating carbonaceous materials containing graphite, assisted by a Diels-Alder reaction | UNIVERSITÉ DE BORDEAUX (FR) | 2017-08-01 | — | — | US | disclosed |
| US-9631096-B2 | Dye compositions, methods of preparation, conjugates thereof, and methods of use | CORNELL UNIVERSITY (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160194207-A1 | METHOD FOR EXFOLIATING CARBONACEAOUS MATERIALS CONTAINING GRAPHITE, ASSISTED BY A DIELS-ALDER REACTION | INSTITUT POLYTECHNIQUE DE BORDEAUX (FR) | 2016-07-07 | — | — | US | disclosed |
| EP-3027555-A2 | METHOD FOR EXFOLIATING CARBONACEOUS MATERIALS CONTAINING GRAPHITE, ASSISTED BY A DIELS-ALDER REACTION | Université de Bordeaux (FR) | 2016-06-08 | — | — | EP | disclosed |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2015-11-19 | — | — | US | disclosed |
| US-8945515-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2015-02-03 | — | — | US | disclosed |
| US-20150011731-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| WO-2013109859-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2013-07-25 | — | — | WO | disclosed |
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2010096720-A2 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, PPOX, PRDX5 | ALDH1A1 525/4885MEN1 1703/4885KMT2A 3610/4885 |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, ARFGEF1, PRDX3 | ALDH1A1 800/4885MEN1 2436/4885KMT2A 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.