SCHEMBL5148556

SCHEMBL5148556

O=CNCCc1cnn2c1N(C(c1ccccc1)(c1ccccc1)c1ccccc1)CC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28752388 0.80
SCHEMBL5147580 0.79 KDM4E (0.34)
SCHEMBL5151713 0.70 NCF1 (0.31)
SCHEMBL5147542 0.67
SCHEMBL5148558 0.67 MEN1 (0.33)
SCHEMBL8763407 0.63 ADH1B (0.46)
SCHEMBL5148524 0.63 ALDH1A1 (0.35)
Ammonia Solution, Strong SCHEMBL5151718 0.62 CYP2B6 (0.32)
SCHEMBL5148585 0.60 MEN1 (0.38)
SCHEMBL8763265 0.59 ADH1B (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7179801-B2 Cephem compounds ASTELLAS PHARMA INC. (JP) 2007-02-20 US disclosed
EP-1392704-B1 CEPHEM COMPOUNDS ASTELLAS PHARMA INC (JP) 2006-02-22 EP disclosed
US-20040248875-A1 Cephem compounds ASTELLAS PHARMA INC. (JP) 2004-12-09 US disclosed
CN-1522259-A Cephem compounds ����ҩƷ��ҵ��ʽ���� 2004-08-18 CN disclosed
EP-1392704-A1 CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-03 EP disclosed
WO-2002090364-A1 CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-14 WO disclosed