Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421115 | 0.90 | TSHR (0.60) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL4810549 | 0.82 | LMNA (0.47) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL11468156 | 0.82 | AKR1B1 (0.60) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL16421113 | 0.82 | GPR84 (0.67) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL9132408 | 0.82 | AKR1B1 (0.54) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL16384725 | 0.80 | GPR84 (0.68) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL21168213 | 0.80 | GPR84 (0.68) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL16418480 | 0.80 | TSHR (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL8202305 | 0.78 | LMNA (0.53) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL1032545 | 0.78 | LMNA (0.53) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070014727-A1 | Contrast media for nuclear spin tomography with use of the overhauser effect | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-01-18 | — | — | US | disclosed |
| WO-2006087144-A2 | CONTRAST AGENTS FOR NUCLEAR SPIN TOMOGRAPHY CARRIED OUT BY MEANS OF OVERHAUSER EFFECT | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-08-24 | — | — | WO | disclosed |