Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6524406 | 0.95 | SNCA (0.55) | SNCAHIF1AAPPSLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL9455086 | 0.90 | SNCA (0.44) | SNCAHIF1AAPPSLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL494 | 0.88 | SNCA (0.63) | SNCAHIF1AAPPSLC6A2TAAR1 | |
| Iodide SCHEMBL31338857 | 0.86 | SNCA (0.49) | SNCAHIF1AAPPSLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL8439240 | 0.86 | PNMT (0.50) | SNCASLC6A2TAAR1SLC6A4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL19994592 | 0.86 | SNCA (0.44) | SNCAHIF1ATAAR1 | |
| Hydrochloric Acid SCHEMBL19371432 | 0.86 | MAOA (0.55) | SNCAHIF1ASLC6A2TAAR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL4224599 | 0.86 | SNCA (0.44) | SNCAHIF1ATAAR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL29427125 | 0.86 | SNCA (0.44) | SNCAHIF1ASLC6A2TAAR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL2447879 | 0.86 | SNCA (0.44) | SNCAHIF1ASLC6A2TAAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282742-B2 | Organic thin film transistor devices and organic photovoltaic devices | TORAY INDUSTRIES, INC. (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20040241900-A1 | Organic semiconductor material and organic semiconductor element employing the same | TORAY INDUSTRIES, INC. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1449887-A1 | ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC SEMICONDUCTOR ELEMENT EMPLOYING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2004-08-25 | — | — | EP | disclosed |