Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 14/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985006 | 0.86 | ITGB1 (0.43) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2985009 | 0.84 | ITGB1 (0.46) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2986983 | 0.81 | ITGB1 (0.49) | ITGB1ITGA4ITGB7 | |
| SCHEMBL3830567 | 0.79 | ELANE (0.37) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2977847 | 0.78 | ITGB1 (0.51) | ITGB1ITGA4ITGB7 | |
| SCHEMBL3837027 | 0.75 | ITGA4 (0.45) | ITGB1ITGA4ITGB7 | |
| SCHEMBL3836888 | 0.72 | ITGB1 (0.46) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2978524 | 0.71 | ITGA4 (0.49) | ITGB1ITGA4ITGB7 | |
| SCHEMBL3830570 | 0.71 | ITGB1 (0.34) | ITGB1ITGA4ITGB7 | |
| SCHEMBL3835537 | 0.70 | FPR2 (0.49) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027174-A1 | Phenylalanine Enamide Derivatives | CELLTECH R&D LIMITED | 2007-02-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027174-A1 | Phenylalanine Enamide Derivatives | PAH, HRH3, AGTR2 | ITGB1 77/4885ITGA4 462/4885ITGB7 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.