SCHEMBL515011

SCHEMBL515011

[CH2]COC(=O)N(C)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.58
CHRNB4 P30926 1/20 0.58
CHRNA3 P32297 1/20 0.58
CHRNA4 P43681 1/20 0.58
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 2/20 0.49
ALDH1A1 P00352 2/20 0.49
KMT2A Q03164 6/20 0.47
MEN1 O00255 4/20 0.47
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL1720409 0.83 CHRNB2 (0.59) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A
SCHEMBL442790 0.83 CHRNB2 (0.59) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A
SCHEMBL5006624 0.81 CHRNB2 (0.58) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A
SCHEMBL28740847 0.81 CHRNB2 (0.58) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A
SCHEMBL88871 0.81 CHRNB2 (0.54) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A
SCHEMBL6002508 0.80 PTGIR (0.41) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL27766401 0.80 CHRNB2 (0.65) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A
SCHEMBL28080593 0.80 CHRNB2 (0.65) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A
SCHEMBL27558112 0.80 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A
SCHEMBL6003209 0.80 NOX1 (0.43) CHRNB2CHRNB4CHRNA3CHRNA4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 CHRNB2 2030/4885CHRNB4 2367/4885CHRNA3 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.