Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151394 | 1.00 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2ATNFRSF1A | |
| SCHEMBL8007239 | 0.89 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ATNFRSF1A | |
| SCHEMBL2226678 | 0.89 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ATNFRSF1A | |
| SCHEMBL8152728 | 0.81 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ATNFRSF1A | |
| SCHEMBL28445243 | 0.81 | HDAC8 (0.55) | MAPTALDH1A1MEN1KMT2AAKR1B10 | |
| SCHEMBL28445241 | 0.81 | HDAC8 (0.55) | MAPTALDH1A1MEN1KMT2AAKR1B10 | |
| SCHEMBL4592405 | 0.81 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ATNFRSF1A | |
| SCHEMBL4592398 | 0.81 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ATNFRSF1A | |
| SCHEMBL31155849 | 0.81 | HDAC8 (0.62) | MAPTALDH1A1MEN1KMT2ATNFRSF1A | |
| SCHEMBL8150697 | 0.79 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2ATNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1738821-A1 | Method of reducing the level of nitrogen oxides in a medium by absorption with resorcin¬4|arenes | British American Tobacco Italia S.p.A. (IT) | 2007-01-03 | — | — | EP | disclosed |