Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | OGT | O15294 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EEF2K | O00418 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952091 | 0.82 | ALDH1A1 (0.62) | L3MBTL1KDM4ETDP1ALDH1A1OGT | |
| SCHEMBL5155289 | 0.82 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1EEF2K | |
| SCHEMBL5151853 | 0.76 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1KMT2AATMEEF2K | |
| SCHEMBL5231642 | 0.76 | CHRM2 (0.54) | ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5155502 | 0.75 | CHRM2 (0.55) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL5803385 | 0.73 | KMT2A (0.58) | L3MBTL1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL5802575 | 0.73 | KMT2A (0.58) | L3MBTL1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL20379845 | 0.68 | PTGS1 (0.59) | L3MBTL1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL22478570 | 0.67 | PTGS1 (0.58) | KDM4EALDH1A1KMT2AMEN1ATM | |
| SCHEMBL12365525 | 0.66 | KDM4E (0.67) | KDM4ETDP1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157454-B2 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2007-01-02 | — | — | US | disclosed |
| US-20040116353-A1 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI (FR) | 2004-06-17 | — | — | US | disclosed |