Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | FPR1 | P21462 | 1/20 | 0.56 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
| ▸ | APLNR | P35414 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | GLP1R | P43220 | 1/20 | 0.56 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | ADGRF1 | Q5T601 | 1/20 | 0.56 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803385 | 1.00 | KMT2A (0.58) | KMT2ACHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL6045001 | 0.93 | CHRM2 (0.56) | KMT2ACHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL6044991 | 0.93 | CHRM2 (0.56) | KMT2ACHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5151853 | 0.88 | L3MBTL1 (0.53) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5155289 | 0.82 | L3MBTL1 (0.61) | ALDH1A1L3MBTL1 | |
| SCHEMBL5803396 | 0.78 | CHRM2 (0.54) | KMT2ACHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5803101 | 0.77 | CHRM2 (0.53) | KMT2ACHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL6045265 | 0.77 | CHRM2 (0.48) | KMT2ACHRM2CHRM5ADRA2CS1PR1 | |
| SCHEMBL5150950 | 0.75 | ALDH1A1 (0.53) | KMT2AALDH1A1MEN1MAPTPKM | |
| SCHEMBL5149094 | 0.75 | CHRM2 (0.71) | CHRM2CHRM5ADRA2CS1PR1FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060217362-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2006-09-28 | — | — | US | disclosed |
| WO-2006071775-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | ELAN PHARMACEUTICALS, INC. (US) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217362-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | KMT2A 4104/4885CHRM2 543/4885CHRM5 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.