Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | INPPL1 | O15357 | 9/20 | 0.50 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.50 |
| ▸ | INPP5B | P32019 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338968 | 0.82 | HTT (0.58) | HTTINPPL1INPP5AINPP5BAKT1 | |
| Menadiol Diphosphoric Acid SCHEMBL1005168 | 0.80 | GPR84 (0.49) | HTTSRCKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL14398797 | 0.74 | SRC (0.47) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL28295682 | 0.74 | GPR84 (0.67) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL1100136 | 0.72 | INPPL1 (0.57) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL8386747 | 0.72 | INPPL1 (0.68) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL10438501 | 0.72 | PLK1 (0.53) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL10915218 | 0.71 | HTT (0.52) | HTTSRCKDM4EHSD17B10TP53 | |
| O-Xylene SCHEMBL29031713 | 0.71 | INPPL1 (0.55) | INPPL1INPP5AINPP5BAKT1SRC | |
| Hydrochloric Acid SCHEMBL11749404 | 0.71 | INPPL1 (0.55) | INPPL1INPP5AINPP5BAKT1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212214-B2 | Methods of increasing the expression yield of vitamin K-dependent proteins | CSL LIMITED (AU) | 2015-12-15 | — | — | US | claimed |
| US-20130261603-A1 | TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS | LUTONIX, INC. (US) | 2013-10-03 | — | — | US | claimed |
| US-20130253475-A1 | TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS | LUTONIX, INC. (US) | 2013-09-26 | — | — | US | claimed |
| US-20130197431-A1 | DRUG RELEASING COATINGS FOR MEDICAL DEVICES | LUTONIX, INC. (US) | 2013-08-01 | — | — | US | claimed |
| US-20130197435-A1 | MEDICAL DEVICE RAPID DRUG RELEASING COATINGS COMPRISING OILS, FATTY ACIDS, AND/OR LIPIDS | LUTONIX, INC. (US) | 2013-08-01 | — | — | US | claimed |
| US-20130189190-A1 | MEDICAL DEVICE RAPID DRUG RELEASING COATINGS COMPRISING A THERAPEUTIC AGENT AND A CONTRAST AGENT | LUTONIX, INC. (US) | 2013-07-25 | — | — | US | claimed |
| US-20130189329-A1 | DRUG RELEASING COATINGS FOR MEDICAL DEVICES | LUTONIX, INC. (US) | 2013-07-25 | — | — | US | claimed |
| US-8414526-B2 | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids | LUTONIX, INC. (US) | 2013-04-09 | — | — | US | claimed |
| US-8414525-B2 | Drug releasing coatings for medical devices | LUTONIX, INC. (US) | 2013-04-09 | — | — | US | claimed |
| EP-2550030-A1 | DRUG RELEASING COATINGS FOR MEDICAL DEVICES | Lutonix, Inc. (US) | 2013-01-30 | — | — | EP | claimed |
| US-20080276935-A1 | TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS | LUTONIX, INC. | 2008-11-13 | — | — | US | claimed |
| US-20080255509-A1 | MEDICAL DEVICE RAPID DRUG RELEASING COATINGS COMPRISING OILS, FATTY ACIDS, AND/OR LIPIDS | LUTONIX, INC. | 2008-10-16 | — | — | US | claimed |
| US-20080255508-A1 | Such as balloon and stents; medical device with overcoating of drug with additive; bioavailability | LUTONIX, INC. | 2008-10-16 | — | — | US | claimed |
| US-20080255510-A1 | Layer containing therapeutic agent, adjuvant and contrast agent ; high speed supplying agent to tissue; adjuvant contains hyfrophilic part and drug affinity part; overcoating exterior surface of medical device | LUTONIX, INC. | 2008-10-16 | — | — | US | claimed |
| US-20080175887-A1 | drug delivering by oral, nasal or pulmonary administration, of rapamycin or paclitaxel drug; additive enhances absorption of drug into body tissue; PEG-fatty acids esters, PEG-fatty alcohol ethers, polyethylene glycol sorbitan fatty acid esters, polyoxyethylene-polyoxypropylene block copolymers | LUTONIX, INC. | 2008-07-24 | — | — | US | claimed |
| WO-2008063581-A2 | TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS | LUTONIX, INC. (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063576-A2 | DRUG RELEASING COATINGS FOR MEDICAL DEVICES | LUTONIX, INC. (US) | 2008-05-29 | — | — | WO | claimed |
| US-20080118544-A1 | Such as a balloon catheter or a stent; a drug not enclosed in micelles or encapsulated in particles or controlled release carriers and an additive having hydrophobic and hydrophilic portions; improved pharmacokinetics and bioavailability | LUTONIX, INC. | 2008-05-22 | — | — | US | claimed |
| EP-0998925-A1 | MEDICINAL COMPOSITIONS FOR TOPICAL ADMINISTRATION CONTAINING VITAMIN D AND VITAMIN K | New Vision Co., Ltd. (JP) | 2000-05-10 | — | — | EP | claimed |
| US-5876709-A | Ophthalmic composition containing active Vitamin D | NEW VISION CO., LTD. (JP) | 1999-03-02 | — | — | US | claimed |