Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515401 | 1.00 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL136359 | 0.97 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL515936 | 0.95 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL10051485 | 0.95 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL515798 | 0.95 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL15422328 | 0.95 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL5110848 | 0.91 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL9171769 | 0.87 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL16099106 | 0.84 | TRIM24 (0.41) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL307414 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285018-A2 | Substituted 9-Amino-Spiro [cycloalkyl[b]quinoline-2,1'cycloalkanes], a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-10-05 | — | — | EP | claimed |
| US-4448712-A | Perfume compositions and perfumed articles containing spiro-undecanones and -undecenones as perfume base | NAARDEN INTERNATIONAL N.V. (NL) | 1984-05-15 | — | — | US | claimed |
| EP-0074693-A1 | Perfume compositions and perfumed articles containing spiro-undecanones and -undecenones as perfume base | NAARDEN INTERNATIONAL N.V. (NL) | 1983-03-23 | — | — | EP | claimed |
| EP-4692071-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025028365-A1 | PHOTOCHROMIC COMPOUND, PHENOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | 株式会社トクヤマ | 2025-02-06 | — | — | WO | disclosed |
| WO-2024202086-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | 株式会社トクヤマ | 2024-10-03 | — | — | WO | disclosed |
| US-20240216516-A1 | GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | TIGER BIOTHERAPEUTICS INC. | 2024-07-04 | — | — | US | disclosed |
| US-11825734-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| US-11825734-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230329090-A1 | SPIRO COMPOUND AND APPLICATION THEREOF | SICHUAN AG-RAY NEW MATERIALS CO., LTD (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20230234936-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | LEADINGTAC PHARMACEUTICAL (SHAOXING) CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-4855479-A | Substituted 9-amino-spiro(cycloalkyl(B)quinoline-2,1'cycloalkanes | SHUTSKE GREGORY M (US) | 1989-08-08 | — | — | US | disclosed |
| US-4814450-A | CENTRAL NERVOUS SYSTEM DISORDERS | CIBA-GEIGY CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| US-4806646-A | Substituted 9-amino-spiro[cycloalkyl[B]quinoline-2,1'cycloalkanes] | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0285018-A2 | Substituted 9-Amino-Spiro [cycloalkyl[b]quinoline-2,1'cycloalkanes], a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4762841-A | Substituted 9-amino-spiro(cycloalkyl(b)quinoline-2,1'cycloalkanes) | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-08-09 | — | — | US | disclosed |
| US-4740512-A | Treating anxiety with certain ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives | CIBA-GEIGY CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |
| US-4647566-A | Certain ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives in treating anxiety | CIBA-GEIGY CORPORATION (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0074693-B1 | PERFUME COMPOSITIONS AND PERFUMED ARTICLES CONTAINING SPIRO-UNDECANONES AND -UNDECENONES AS PERFUME BASE | NAARDEN INTERNATIONAL N.V. (NL) | 1986-01-08 | — | — | EP | disclosed |
| US-4448712-A | Perfume compositions and perfumed articles containing spiro-undecanones and -undecenones as perfume base | NAARDEN INTERNATIONAL N.V. (NL) | 1984-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216516-A1 | GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | KRAS, VHL, HRAS | TRIM24 2729/4885TRIM33 602/4885ALDH1A1 1085/4885 |
| US-20230234936-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | IRAK4, IRAK2, IRAK1 | TRIM24 105/4885TRIM33 395/4885ALDH1A1 3835/4885 |
| US-11825734-B2 | Organic electroluminescent materials and devices | OCIAD2, OCIAD1, OSBP | TRIM24 3563/4885TRIM33 4475/4885ALDH1A1 896/4885 |
| US-20230329090-A1 | SPIRO COMPOUND AND APPLICATION THEREOF | SELL, SORD, TRPV4 | TRIM24 2483/4885TRIM33 4790/4885ALDH1A1 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.