Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515266 | 1.00 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL136359 | 0.97 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL515936 | 0.95 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL10051485 | 0.95 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL515798 | 0.95 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL15422328 | 0.95 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL5110848 | 0.91 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL9171769 | 0.87 | TRIM24 (0.44) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL16099106 | 0.84 | TRIM24 (0.41) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL307414 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403777-B2 | Inhibitors of the influenza A virus M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-08-02 | — | — | US | disclosed |
| US-9403777-B2 | Inhibitors of the influenza A virus M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-08-02 | — | — | US | disclosed |
| US-9403777-B2 | Inhibitors of the influenza A virus M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-08-02 | — | — | US | disclosed |
| US-20140024635-A1 | INHIBITORS OF THE INFLUENZA A VIRUS M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-01-23 | — | — | US | disclosed |
| US-20140024635-A1 | INHIBITORS OF THE INFLUENZA A VIRUS M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-01-23 | — | — | US | disclosed |
| US-20140024635-A1 | INHIBITORS OF THE INFLUENZA A VIRUS M2 PROTON CHANNEL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-01-23 | — | — | US | disclosed |
| US-8569284-B2 | Inhibitors of the influenza A virus M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569284-B2 | Inhibitors of the influenza A virus M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569284-B2 | Inhibitors of the influenza A virus M2 proton channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120028957-A1 | Inhibitors Of The Influenza A Virus M2 Proton Channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2012-02-02 | — | — | US | disclosed |
| US-20120028957-A1 | Inhibitors Of The Influenza A Virus M2 Proton Channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2012-02-02 | — | — | US | disclosed |
| US-20120028957-A1 | Inhibitors Of The Influenza A Virus M2 Proton Channel | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2012-02-02 | — | — | US | disclosed |
| EP-0310321-B1 | Immunomodulatory azaspiranes | SMITHKLINE BEECHAM CORP (US) | 1994-11-30 | — | — | EP | disclosed |
| EP-0310321-A2 | Immunomodulatory azaspiranes | SMITHKLINE BEECHAM CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028957-A1 | Inhibitors Of The Influenza A Virus M2 Proton Channel | HVCN1, ATP6AP1, ASIC1 | TRIM24 2676/4885TRIM33 4489/4885ALDH1A1 2559/4885 |
| US-20140024635-A1 | INHIBITORS OF THE INFLUENZA A VIRUS M2 PROTON CHANNEL | HVCN1, ATP6AP1, ASIC1 | TRIM24 2676/4885TRIM33 4489/4885ALDH1A1 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.