⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455034 | 1.00 | — | — | |
| Acetamide SCHEMBL29160426 | 0.87 | ALOX15 (0.40) | — | |
| SCHEMBL13132156 | 0.75 | — | — | |
| SCHEMBL6236986 | 0.75 | — | — | |
| Hydrazine SCHEMBL11440109 | 0.73 | — | — | |
| Hydrazine SCHEMBL11440104 | 0.73 | ALOX15 (0.30) | — | |
| SCHEMBL1286909 | 0.73 | ALDH1A1 (0.40) | — | |
| SCHEMBL4292157 | 0.72 | — | — | |
| SCHEMBL107804 | 0.72 | — | — | |
| SCHEMBL8121081 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511915-A | Remedies for glycogen disease type Ia | 第一三共株式会社 | 2020-08-07 | — | — | CN | disclosed |
| CN-105705638-B | What is improved has dynamical nanoparticle form oligonucleotide structure and preparation method thereof | 柏业公司 | 2019-11-26 | — | — | CN | disclosed |
| CN-109983128-A | Oligonucleotide composition and its method | 波涛生命科学有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109952378-A | Modified oligonucleotides and application method | 詹森生物制药有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109943549-A | A kind of ultrahigh speed amplification type Taq archaeal dna polymerase | 苏州译酶生物科技有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109517063-A | Target the composition and method of the antibody of EPO | 诺华股份有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-104968669-B | Synthesis of deuterated ribonucleosides, N-protected phosphoramidites and oligonucleotides | 阿萨德有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-109477108-A | Oligonucleotide composition and its method | 波涛生命科学有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109153860-A | Ultra-high brightness dimeric or polymeric dyes with spacer linker groups | 索尼公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-104968678-B | Compositions and methods of antibodies targeting EPO | 诺华股份有限公司 | 2018-12-11 | — | — | CN | disclosed |
| WO-2002069898-A2 | COMPOSITIONS AND METHODS USING PLATINUM COMPOUNDS FOR NUCLEIC ACID LABELING | STRATAGENE (US) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002068537-A2 | FLUORESCENT DYE | STRATAGENE (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002028428-A2 | VACCINE COMPOSITION | AVENTIS PASTEUR (FR) | 2002-04-11 | — | — | WO | disclosed |
| EP-1121148-A2 | IMMUNOSTIMULANT EMULSION | Aventis Pasteur (FR) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000015256-A2 | IMMUNOSTIMULANT EMULSION | AVENTIS PASTEUR (FR) | 2000-03-23 | — | — | WO | disclosed |
| US-5981747-A | FOR USE AS FLUORESCENT MARKERS | CARNEGIE MELLON UNIVERSITY (US) | 1999-11-09 | — | — | US | disclosed |
| CN-1131951-A | Building blocks with carbamate internucleoside linkages and novel ligonucleotides derived therefrom | HYBRIDON INC (US) | 1996-09-25 | — | — | CN | disclosed |
| EP-0604409-A4 | COMPOSITIONS AND METHODS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION. | ISIS PHARMACEUTICALS INC (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0604409-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 1994-07-06 | — | — | EP | disclosed |
| WO-1991010671-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 1991-07-25 | — | — | WO | disclosed |