Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236986 | 0.98 | — | — | |
| SCHEMBL26685597 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL1115916 | 0.78 | MEN1 (0.55) | ALDH1A1TSHRTHRB | |
| SCHEMBL844249 | 0.78 | MEN1 (0.55) | ALDH1A1TSHRTHRB | |
| SCHEMBL30688068 | 0.78 | MEN1 (0.55) | ALDH1A1TSHRTHRB | |
| SCHEMBL8446691 | 0.78 | MEN1 (0.55) | ALDH1A1TSHRTHRB | |
| SCHEMBL9056856 | 0.78 | MEN1 (0.55) | ALDH1A1TSHRTHRB | |
| SCHEMBL29249765 | 0.77 | — | — | |
| SCHEMBL5603804 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL13132156 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9243023-B2 | Purification of synthetic oligonucleotides | MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 2016-01-26 | — | — | US | disclosed |
| US-20130211065-A1 | PURIFICATION OF SYNTHETIC OLIGONUCLEOTIDES | MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 2013-08-15 | — | — | US | disclosed |
| US-8283455-B2 | Reagent compounds and methods of making same | LC SCIENCES LC | 2012-10-09 | — | — | US | disclosed |
| WO-2012047639-A2 | PURIFICATION OF SYNTHETIC OLIGONUCLEOTIDES | MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 2012-04-12 | — | — | WO | disclosed |
| US-20110288285-A1 | Novel reagent compounds and methods of making same | LC SCIENCES LC | 2011-11-24 | — | — | US | disclosed |
| US-7923550-B2 | Reagent compounds and methods of making and using the same | LC SCIENCES LC | 2011-04-12 | — | — | US | disclosed |
| US-20110082288-A1 | PURIFICATION OF SYNTHETIC OLIGOMERS | MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 2011-04-07 | — | — | US | disclosed |
| US-7850949-B2 | Purification of synthetic oligomers | MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 2010-12-14 | — | — | US | disclosed |
| WO-2008067026-A2 | PURIFICATION OF SYNTHETIC OLIGOMERS | MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080081902-A1 | PURIFICATION OF SYNTHETIC OLIGOMERS | MICHIGAN TECHNOLOGICAL UNIVERSITY | 2008-04-03 | — | — | US | disclosed |
| US-20070060536-A1 | Novel reagent compounds and methods of making and using the same | UNIVERSITY OF HOUSTON (US) | 2007-03-15 | — | — | US | disclosed |
| WO-2005000859-A2 | NOVEL REAGENT COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF HOUSTON (US) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082288-A1 | PURIFICATION OF SYNTHETIC OLIGOMERS | RNGTT, NOP2, CAPZA2 | ALDH1A1 4461/4885TSHR 4552/4885THRB 4326/4885 |
| US-20080081902-A1 | PURIFICATION OF SYNTHETIC OLIGOMERS | RNGTT, NOP2, CAPZA2 | ALDH1A1 4461/4885TSHR 4552/4885THRB 4326/4885 |
| US-20070060536-A1 | Novel reagent compounds and methods of making and using the same | HLCS, PTMS, CD2BP2 | ALDH1A1 2942/4885TSHR 3156/4885THRB 4211/4885 |
| US-20130211065-A1 | PURIFICATION OF SYNTHETIC OLIGONUCLEOTIDES | RNGTT, NOP2, NSUN2 | ALDH1A1 4472/4885TSHR 2459/4885THRB 3680/4885 |
| US-20110288285-A1 | Novel reagent compounds and methods of making same | HLCS, PTMS, CD2BP2 | ALDH1A1 3200/4885TSHR 3219/4885THRB 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.