Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamonitrile SCHEMBL996307 | 0.84 | KDM4E (0.54) | KDM4ETRPA1ENPP2NFE2L2CYP1A2 | |
| Cinnamonitrile SCHEMBL23599 | 0.84 | KDM4E (0.54) | KDM4ETRPA1ENPP2NFE2L2CYP1A2 | |
| Cinnamonitrile SCHEMBL23933 | 0.84 | KDM4E (0.54) | KDM4ETRPA1ENPP2NFE2L2CYP1A2 | |
| Cinnamonitrile SCHEMBL27473675 | 0.80 | KDM4E (0.62) | KDM4ETRPA1ENPP2FDPSNFE2L2 | |
| SCHEMBL11304576 | 0.80 | KDM4E (0.55) | KDM4ETRPA1ENPP2NFE2L2MAOB | |
| Water SCHEMBL27875443 | 0.78 | TRPA1 (0.52) | KDM4ETRPA1NFE2L2TUBB1TUBB4A | |
| Cinnamonitrile SCHEMBL28165460 | 0.76 | ENPP2 (0.50) | KDM4ETRPA1ENPP2NFE2L2CYP1A2 | |
| Cinnamonitrile SCHEMBL28064832 | 0.76 | KDM4E (0.47) | KDM4ETRPA1ENPP2FDPSNFE2L2 | |
| Cinnamonitrile SCHEMBL5153011 | 0.76 | KDM4E (0.41) | KDM4ETRPA1ENPP2FDPSNFE2L2 | |
| SCHEMBL14910 | 0.75 | TRPA1 (0.54) | KDM4ETRPA1NFE2L2TUBB1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558617-A4 | AMIDINE COMPOUNDS | UNIV MONASH (AU) | 2007-07-11 | — | — | EP | disclosed |
| EP-1558617-A1 | AMIDINE COMPOUNDS | Monash University (AU) | 2005-08-03 | — | — | EP | disclosed |
| EP-1423392-A4 | DERIVATIVES OF MORPHINE-LIKE OPIOID COMPOUNDS | POLYCHIP PHARMACEUTICALS PTY (AU) | 2004-11-17 | — | — | EP | disclosed |
| EP-1423392-A1 | DERIVATIVES OF MORPHINE-LIKE OPIOID COMPOUNDS | Polychip Pharmaceuticals Pty. Ltd. (AU) | 2004-06-02 | — | — | EP | disclosed |
| WO-2004033458-A1 | AMIDINE COMPOUNDS | MONASH UNIVERSITY (AU) | 2004-04-22 | — | — | WO | disclosed |
| WO-2003014122-A1 | DERIVATIVES OF MORPHINE-LIKE OPIOID COMPOUNDS | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 2003-02-20 | — | — | WO | disclosed |