Nitrogen

Nitrogen

SCHEMBL8501917

COc1cccc([N+](=O)[O-])c1.N#N

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 2/20 0.58
LMNA P02545 2/20 0.57
TSHR P16473 2/20 0.57
MAPT P10636 6/20 0.55
ALDH1A1 P00352 4/20 0.55
CHRNB2 P17787 1/20 0.54
CHRNA4 P43681 1/20 0.54
ACHE P22303 1/20 0.53
GPR17 Q13304 1/20 0.53
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
MAOB P27338 1/20 0.52
KEAP1 Q14145 1/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
POLB P06746 1/20 0.51
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL8500176 0.98 NFE2L2 (0.56) NFE2L2LMNATSHRMAPTALDH1A1
SCHEMBL515302 0.96 LMNA (0.61) NFE2L2LMNATSHRMAPTALDH1A1
SCHEMBL30059246 0.96 LMNA (0.61) NFE2L2LMNATSHRMAPTALDH1A1
SCHEMBL28218708 0.96 LMNA (0.61) NFE2L2LMNATSHRMAPTALDH1A1
Cyanide SCHEMBL27784323 0.95 NFE2L2 (0.56) NFE2L2LMNATSHRMAPTALDH1A1
SCHEMBL28090002 0.94 NFE2L2 (0.59) NFE2L2LMNATSHRMAPTALDH1A1
SCHEMBL30612688 0.94 NFE2L2 (0.59) NFE2L2LMNATSHRMAPTALDH1A1
Methylamine SCHEMBL11814441 0.93 NFE2L2 (0.58) NFE2L2LMNATSHRMAPTALDH1A1
Anisole SCHEMBL28873619 0.91 NFE2L2 (0.60) NFE2L2LMNATSHRMAPTALDH1A1
Hydrazine SCHEMBL28200766 0.91 NFE2L2 (0.56) NFE2L2LMNATSHRMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599270-B1 Method of detecting phosphatase AISIN SEIKI (JP) 1999-05-12 EP claimed
EP-0599270-A2 Method of detecting phosphatase AISIN SEIKI KABUSHIKI KAISHA (JP) 1994-06-01 EP claimed
EP-0132313-B1 REAGENTS, TEST KITS AND METHODS FOR THE DETECTION OF CANNABINOIDS EREZ FORENSIC TECHNOLOGY LTD. (IL) 1991-09-18 EP claimed
EP-0599270-B1 Method of detecting phosphatase AISIN SEIKI (JP) 1999-05-12 EP disclosed
US-5480791-A Method of detecting phosphatase AISIN SEIKI KABUSHIKI KAISHA (JP) 1996-01-02 US disclosed
EP-0599270-A2 Method of detecting phosphatase AISIN SEIKI KABUSHIKI KAISHA (JP) 1994-06-01 EP disclosed
US-4157892-A COLORING AGENT IS CHEMICALLY COUPLED TO POLYMER TOYO CONTACT LENS COMPANY, LIMITED (JP) 1979-06-12 US disclosed