SCHEMBL5153894

SCHEMBL5153894

CCCCCCCCCCCCn1c2ccccc2c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.64
RORA P35398 1/20 0.64
RORC P51449 1/20 0.64
RORB Q92753 1/20 0.64
MAOA P21397 11/20 0.60
MAOB P27338 11/20 0.60
GRIN1 Q05586 9/20 0.60
GRIN2A Q12879 9/20 0.60
GRIN2B Q13224 9/20 0.60
ACHE P22303 3/20 0.60
CNR2 P34972 1/20 0.60
PSEN1 P49768 3/20 0.59
PSEN2 P49810 3/20 0.59
APH1B Q8WW43 3/20 0.59
NCSTN Q92542 3/20 0.59
APH1A Q96BI3 3/20 0.59
PSENEN Q9NZ42 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29311733 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL6575875 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL29490761 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL6275417 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL6774209 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL6278388 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL1000878 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL1001993 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL750975 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL29557199 1.00 PGR (0.64) PGRRORARORCRORBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5350633-A Carbazole derivative desensitizer SAKURA COLOR PRODUCTS CORPORATION (JP) 1994-09-27 US claimed
CN-110003089-B 3-hydroxymethyl-9-substituted carbazole and preparation method thereof 陕西科技大学 2022-07-01 CN disclosed
CN-112500390-B Organic hole transport material, synthesis method thereof and perovskite battery 隆基绿能科技股份有限公司 2022-06-10 CN disclosed
CN-109553568-B Conjugated alkynyl anthracene derivative and method for regulating atom transfer radical polymerization by using same as visible light photosensitizer 安庆北化大科技园有限公司 2022-05-03 CN disclosed
CN-112500390-A Organic hole transport material, synthesis method thereof and perovskite battery 隆基绿能科技股份有限公司 2021-03-16 CN disclosed
CN-108931886-A Curable adhensive compositions, hardenite and liquid crystal display element 捷恩智株式会社 2018-12-04 CN disclosed
CN-101381364-B Starburst molecule containing 2,4,6-tri(2-thineyl)-1,3,5-s-triazine unit and preparation method thereof and use UNIV WUHAN 2010-12-22 CN disclosed
CN-101381364-A Starburst molecule containing 2,4,6-tri(2-thineyl)-1,3,5-s-triazine unit and preparation method thereof and use UNIV WUHAN (CN) 2009-03-11 CN disclosed
EP-1519239-B1 Organophotoreceptor with a charge transport material having at least two azine groups SAMSUNG ELECTRONICS CO LTD (KR) 2007-01-03 EP disclosed
US-20050069798-A1 Organophotoreceptor with a charge transport material having two azine groups S-PRINTING SOLUTION CO., LTD. (KR) 2005-03-31 US disclosed
EP-1519239-A2 Organophotoreceptor with a charge transport material having at least two azine groups Samsung Electronics Co., Ltd. (KR) 2005-03-30 EP disclosed
US-6864025-B2 Sulfonyldiphenylene-based charge transport compositions SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-03-08 US disclosed
US-6835513-B2 An organophotoreceptor comprising: (a) a charge transport compound having the formula carbazole compound dispersion of colorant particles in an organic liquid and charge transport compound having the formula of carbazole compound SAMSUNG ELECTRONIC CO., LTD. (KR) 2004-12-28 US disclosed
US-20030207188-A1 Carbazole based charge transport compounds S-PRINTING SOLUTION CO., LTD. (KR) 2003-11-06 US disclosed
US-20030203296-A1 Sulfonyldiphenylene-based charge transport compositions S-PRINTING SOLUTION CO., LTD. (KR) 2003-10-30 US disclosed
US-6340548-B1 HIGH QUALITY OF THE IMAGES IS MAINTAINED AFTER REPEATED CYCLING IMATION CORP. 2002-01-22 US disclosed
WO-2001071430-A1 ORGANOPHOTORECEPTORS FOR ELECTROPHOTOGRAPHY COMPRISING HYDRAZONE CHARGE TRANSPORT COMPOUNDS IMATION CORP. (US) 2001-09-27 WO disclosed
US-5350633-A Carbazole derivative desensitizer SAKURA COLOR PRODUCTS CORPORATION (JP) 1994-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207188-A1 Carbazole based charge transport compounds SLC33A1, SLC43A1, AHR PGR 1083/4885RORA 722/4885RORC 721/4885
US-20050069798-A1 Organophotoreceptor with a charge transport material having two azine groups NR2E3, CHRM4, CHRM3 PGR 760/4885RORA 2108/4885RORC 2521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.