Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998208 | 0.91 | AKR1C2 (0.46) | POLBMAPTHPGDCNR1PTGDR | |
| SCHEMBL18765238 | 0.87 | POLB (0.38) | POLBMAPTHPGDCNR1PTGDR | |
| SCHEMBL5154300 | 0.87 | POLB (0.38) | POLBMAPTHPGDCNR1PTGDR | |
| SCHEMBL5806535 | 0.86 | POLB (0.41) | POLBMAPTHPGDCNR1MRGPRX4 | |
| SCHEMBL8671570 | 0.85 | POLB (0.40) | POLBMAPTHPGDCNR1MRGPRX4 | |
| SCHEMBL4691290 | 0.85 | PTGS1 (0.44) | POLBMAPTHPGDCNR1PTGDR | |
| Hydrochloric Acid SCHEMBL5805761 | 0.84 | KRAS (0.43) | POLBMAPTHPGDCNR1MRGPRX4 | |
| SCHEMBL5809614 | 0.84 | MEN1 (0.40) | POLBMAPTHPGDPTGDRPTGDR2 | |
| SCHEMBL5806286 | 0.84 | POLB (0.35) | POLBMAPTHPGDCNR1PTGDR | |
| SCHEMBL7761162 | 0.84 | PTGS2 (0.39) | POLBMAPTHPGDCNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610776-A4 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | MERCK & CO INC (US) | 2007-03-28 | — | — | EP | disclosed |
| EP-1610776-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | Merck & Co. Inc. (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087051-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | MERCK & CO., INC. (US) | 2004-10-14 | — | — | WO | disclosed |