Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691290 | 0.86 | PTGS1 (0.44) | PTGS2POLBMAPTTP53HPGD | |
| SCHEMBL5809569 | 0.86 | PTGS2 (0.48) | PTGS2POLBMAPTKMT2AMEN1 | |
| SCHEMBL4694469 | 0.84 | PTGS2 (0.37) | PTGS2POLBMAPTTP53HPGD | |
| SCHEMBL5805773 | 0.84 | PTGS2 (0.47) | PTGS2POLBMAPTL3MBTL1KMT2A | |
| SCHEMBL5806535 | 0.84 | POLB (0.41) | POLBMAPTTSHRHPGDCNR1 | |
| SCHEMBL5154201 | 0.84 | POLB (0.41) | POLBMAPTKMT2AMEN1HPGD | |
| SCHEMBL998208 | 0.84 | AKR1C2 (0.46) | PTGS2POLBMAPTKMT2AMEN1 | |
| SCHEMBL5805756 | 0.83 | PTGS2 (0.47) | PTGS2MAPTKMT2AMEN1TP53 | |
| SCHEMBL5809313 | 0.82 | PTGS2 (0.42) | PTGS2POLBMAPTKMT2AMEN1 | |
| SCHEMBL8673269 | 0.81 | POLB (0.33) | PTGS2POLBMAPTHPGDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001062085-A1 | PROTECTED FORMS OF PHARMACOLOGICALLY ACTIVE AGENTS AND USES THEREFOR | MEDINOX, INC. (US) | 2001-08-30 | — | — | WO | disclosed |