Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027480 | 1.00 | ATM (0.48) | ATMCES2CES1ESR1ESR2 | |
| SCHEMBL515423 | 1.00 | ATM (0.48) | ATMCES2CES1ESR1ESR2 | |
| SCHEMBL498532 | 0.83 | ATM (0.52) | ATMCES2CES1ESR1ESR2 | |
| SCHEMBL7803887 | 0.81 | CES2 (0.50) | ATMCES2CES1ESR1HDAC1 | |
| SCHEMBL16787362 | 0.81 | ATM (0.45) | ATMCES2CES1ESR1ESR2 | |
| SCHEMBL17188467 | 0.81 | MAOA (0.57) | ATMCES2CES1ESR1ESR2 | |
| SCHEMBL17188465 | 0.81 | ATM (0.45) | ATMCES2CES1ESR1ESR2 | |
| SCHEMBL22567026 | 0.81 | ATM (0.45) | ATMCES2CES1ESR1ESR2 | |
| SCHEMBL6159704 | 0.81 | ATM (0.45) | ATMCES2CES1ESR1ESR2 | |
| SCHEMBL7803886 | 0.81 | CES2 (0.50) | ATMCES2CES1ESR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240044832-A1 | METHODS FOR DIAGNOSING CANCER BASED ON VOLATILE ORGANIC COMPOUNDS IN BLOOD AND URINE SAMPLES | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (IL) | 2024-02-08 | — | — | US | claimed |
| EP-4264260-A1 | METHODS FOR DIAGNOSING CANCER BASED ON VOLATILE ORGANIC COMPOUNDS IN BLOOD AND URINE SAMPLES | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2023-10-25 | — | — | EP | claimed |
| WO-2022137232-A1 | METHODS FOR DIAGNOSING CANCER BASED ON VOLATILE ORGANIC COMPOUNDS IN BLOOD AND URINE SAMPLES | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (IL) | 2022-06-30 | — | — | WO | claimed |
| CN-113136239-B | Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond | 清华大学 | 2022-05-13 | — | — | CN | claimed |
| US-11224241-B2 | Methods and compositions for affecting the flavor and aroma profile of consumables | IMPOSSIBLE FOODS INC. (US) | 2022-01-18 | — | — | US | claimed |
| US-11219232-B2 | Methods and compositions for affecting the flavor and aroma profile of consumables | IMPOSSIBLE FOODS INC. (US) | 2022-01-11 | — | — | US | claimed |
| US-11040925-B2 | 3-(5-substituted-4-oxoquinazolin-3(4H)-yl)-3-deutero-piperidine-2,6-dione derivatives and compositions comprising and methods of using the same | DEUTERX, LLC (US) | 2021-06-22 | — | — | US | claimed |
| US-20190330124-A1 | 3-(5-SUBSTITUTED-4-OXOQUINAZOLIN-3(4H)-YL)-3-DEUTERO-PIPERIDINE-2,6-DIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | SALARIUS PHARMACEUTICALS, INC. | 2019-10-31 | — | — | US | claimed |
| US-10327464-B2 | Methods and compositions for affecting the flavor and aroma profile of consumables | IMPOSSIBLE FOODS INC. (US) | 2019-06-25 | — | — | US | claimed |
| US-10314325-B2 | Methods and compositions for affecting the flavor and aroma profile of consumables | IMPOSSIBLE FOODS INC. (US) | 2019-06-11 | — | — | US | claimed |
| EP-2943201-A1 | 3-(5-SUBSTITUTED-4-OXOQUINAZOLIN-3(4H)-YL)-3-DEUTERO-PIPERIDINE-2,6-DIONE DERIVATIVES | Deuterx, LLC (US) | 2015-11-18 | — | — | EP | claimed |
| WO-2014110558-A1 | 3-(5-SUBSTITUTED-4-OXOQUINAZOLIN-3(4H)-YL)-3-DEUTERO-PIPERIDINE-2,6-DIONE DERIVATIVES | DEUTERX, LLC (US) | 2014-07-17 | — | — | WO | claimed |
| US-20110288191-A1 | MACROPOROUS ABSORBENT RESIN FOR EXTRACTING CEPHALOSPORIN C AND METHOD OF PREPARATION | WANG LING (CN) | 2011-11-24 | — | — | US | claimed |
| EP-2319618-A1 | MACROPOROUS ADSORPTION RESIN SPECIAL FOR EXTRACTING CEPHALOSPORIN C AND ITS PREPARATION METHOD | Shandong Lukang Record Pharmaceutical Co., Ltd (CN) | 2011-05-11 | — | — | EP | claimed |
| CN-1291977-C | Polysubstituted quinazine derivative funcional material, and preparing method and thereof | UNIV FUDAN (CN) | 2006-12-27 | — | — | CN | claimed |
| CN-1528748-A | Polysubstituted quinazine derivative funcional material, and preparing method and thereof | 复旦大学 | 2004-09-15 | — | — | CN | claimed |
| EP-0992559-B1 | Flame retardant adhesive composition | DU PONT (US) | 2003-10-15 | — | — | EP | claimed |
| EP-2943072-B2 | METHODS FOR AFFECTING THE FLAVOUR AND AROMA PROFILE OF CONSUMABLES | IMPOSSIBLE FOODS INC (US) | 2025-04-30 | — | — | EP | disclosed |
| US-3975278-A | Tractants comprising linear dimers of α-alkyl styrene | MONSANTO COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3946081-A | OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040925-B2 | 3-(5-substituted-4-oxoquinazolin-3(4H)-yl)-3-deutero-piperidine-2,6-dione derivatives and compositions comprising and methods of using the same | IL5, TLR5, IDO1 | ATM 3544/4885CES2 4618/4885CES1 3731/4885 |
| US-20190330124-A1 | 3-(5-SUBSTITUTED-4-OXOQUINAZOLIN-3(4H)-YL)-3-DEUTERO-PIPERIDINE-2,6-DIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | IL5, TLR5, IDO1 | ATM 3544/4885CES2 4618/4885CES1 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.