Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491708 | 0.86 | ALDH1A1 (0.39) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| Water SCHEMBL3203989 | 0.84 | ALDH1A1 (0.38) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL3220018 | 0.84 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL195067 | 0.81 | — | — | |
| SCHEMBL7987882 | 0.80 | HPGD (0.35) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL72463 | 0.78 | MEN1 (0.36) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL11244693 | 0.78 | HPGD (0.34) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL16000680 | 0.78 | GAA (0.42) | GAAALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL7991035 | 0.76 | HDAC3 (0.46) | KDM4EGAAMAPTALDH1A1HSD17B10 | |
| SCHEMBL20742632 | 0.76 | CYP2D6 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174151-B1 | THERAPEUTIC TREATMENT OF EOSINOPHILIA USING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT | DAIICHI ASUBIO PHARMA CO LTD (JP) | 2007-01-24 | — | — | EP | claimed |
| EP-0282079-B1 | COATING COMPOSITION WITH IMPROVED RUST-PREVENTING PROPERTIES FOR USE IN PREPARING LUBRICATED STEEL PRODUCTS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1993-03-03 | — | — | EP | claimed |
| CN-111689977-A | Camptothecin 20-position modified sulfonylurea compound and preparation method and application thereof | 兰州大学 | 2020-09-22 | — | — | CN | disclosed |
| EP-0282079-B1 | COATING COMPOSITION WITH IMPROVED RUST-PREVENTING PROPERTIES FOR USE IN PREPARING LUBRICATED STEEL PRODUCTS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4826902-A | SULFONAMIDE-CARBOXYLIC ACID AND CYCLIC AMINE STABILIZER | NIPPON OIL & FATS CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0282079-A2 | Coating composition with improved rust-preventing properties for use in preparing lubricated steel products | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |