Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491708 | 0.93 | ALDH1A1 (0.39) | PTPN1AKR1B1 | |
| Water SCHEMBL3203989 | 0.91 | ALDH1A1 (0.38) | PTPN1AKR1B1 | |
| SCHEMBL8091952 | 0.84 | FAAH (0.43) | PTPN1FAAHCES2 | |
| SCHEMBL5154677 | 0.84 | KDM4E (0.35) | PTPN1 | |
| SCHEMBL13113281 | 0.83 | FAAH (0.41) | PTPN1FAAHCES2 | |
| Carbamic Acid SCHEMBL10399044 | 0.82 | PTPN1 (0.40) | PTPN1FAAH | |
| SCHEMBL1347954 | 0.81 | RELA (0.41) | FAAH | |
| SCHEMBL9675528 | 0.81 | FAAH (0.40) | PTPN1FAAH | |
| SCHEMBL4668386 | 0.81 | FAAH (0.45) | PTPN1FAAHCES2 | |
| SCHEMBL4296201 | 0.81 | FAAH (0.45) | PTPN1FAAHCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | claimed |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-10 | — | — | US | claimed |
| EP-0968193-B1 | PHENYLSULPHONYL UREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2007-02-21 | — | — | EP | claimed |
| EP-0900023-B1 | SUBSTITUTED AMINOMETHYL PHENYL SULPHONYL UREAS, THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2002-11-27 | — | — | EP | claimed |
| EP-0575503-B1 | HERBICIDAL PYRIDINE SULFONAMIDE | DU PONT (US) | 1999-11-24 | — | — | EP | claimed |
| US-5925596-A | PRE-EMERGENCE AND POST-EMERGENCE HERBICIDES | HOECHST-SCHERING AGREVO GMBH (DE) | 1999-07-20 | — | — | US | claimed |
| EP-0502740-B1 | Herbicidal pyridine sulfonamide | DU PONT (US) | 1998-05-27 | — | — | EP | claimed |
| US-5380910-A | Dehalogeno coupling | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-01-10 | — | — | US | claimed |
| EP-0575503-A1 | HERBICIDAL PYRIDINE SULFONAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-29 | — | — | EP | claimed |
| WO-1992015576-A1 | HERBICIDAL PYRIDINE SULFONAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | claimed |
| EP-0502740-A1 | Herbicidal pyridine sulfonamide | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-09 | — | — | EP | claimed |
| EP-0169815-B1 | N-ARYLSULFONYL-N'-TRIAZINYL- AND -PYRIMIDINYL UREAS | CIBA-GEIGY AG (CH) | 1988-11-02 | — | — | EP | claimed |
| EP-0139612-B1 | HERBICIDAL AGENT | CIBA-GEIGY AG (CH) | 1988-02-10 | — | — | EP | claimed |
| EP-0084020-B1 | N-ARYLSULFONYL-N'-PYRIMIDINYL UREAS | CIBA-GEIGY AG (CH) | 1987-09-16 | — | — | EP | claimed |
| JP-6298723-A | — | — | None | — | — | JP | disclosed |
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | disclosed |
| US-20090270631-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2009-10-29 | — | — | US | disclosed |
| EP-0007567-A1 | Aqueous hydraulic liquid and concentrates thereof having improved corrosion-protective properties for metals | Theunissen, Helmut (DE) | 1980-02-06 | — | — | EP | disclosed |
| US-3933894-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933894-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270631-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | PTPN1 596/4885FAAH 1354/4885AKR1B1 121/4885 |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | FABP4, SLC5A1, SLC5A2 | PTPN1 583/4885FAAH 955/4885AKR1B1 59/4885 |
| US-20100041892-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | PTPN1 596/4885FAAH 1354/4885AKR1B1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.