Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736712 | 0.93 | CYP2A6 (0.42) | CYP2A6TYRUSP2GAAALOX15 | |
| SCHEMBL9736014 | 0.79 | TLR8 (0.49) | CYP2A6BACE1GPR84APPMAPT | |
| SCHEMBL1545052 | 0.77 | TLR8 (0.54) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL19506397 | 0.77 | TYR (0.46) | CYP2A6TYRUSP2GAAALOX15 | |
| SCHEMBL9736443 | 0.77 | KDM4E (0.40) | CYP2A6GAABACE1GPR84APP | |
| SCHEMBL9735764 | 0.77 | KDM4E (0.40) | CYP2A6GAABACE1GPR84APP | |
| SCHEMBL1702125 | 0.75 | BACE1 (0.42) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL13934407 | 0.74 | CYP2A6 (0.50) | CYP2A6TYRUSP2GAAALOX15 | |
| SCHEMBL31375356 | 0.73 | TYR (0.58) | CYP2A6TYRUSP2GAAALOX15 | |
| SCHEMBL31375351 | 0.73 | TYR (0.58) | CYP2A6TYRUSP2GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113520913-B | Hair dye containing silica nanoparticles loaded with dihydroxyindole carboxylic acid | 绍兴孚原生物科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-113520913-A | Hair dye containing silica nanoparticles loaded with dihydroxyindole carboxylic acid | 绍兴孚原生物科技有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-111089923-A | Extraction and detection method of 5,6-dihydroxyindole carboxylic acid | 河北大学 | 2020-05-01 | — | — | CN | claimed |
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| CN-116555446-B | DCT gene molecular marker related to black peritoneum character of chicken and application | 华南农业大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-117264078-A | Conjugated polypeptide of transdermal enhanced peptide and glutathione and application thereof | 齐鲁工业大学(山东省科学院) | 2023-12-22 | — | — | CN | disclosed |
| CN-116715727-A | Flower gum small molecule active peptide and application thereof | 大连深蓝肽科技研发有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-114788796-B | Whitening and antibacterial cosmetic containing Fuding white tea extract and preparation method thereof | 河南省纳普生物技术有限公司 | 2023-08-25 | — | — | CN | disclosed |
| US-20230255934-A1 | NURR1 RECEPTOR MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-17 | — | — | US | disclosed |
| CN-116555446-A | DCT gene molecular marker related to black peritoneum character of chicken and application | 华南农业大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116500175-A | Method for measuring content of melanin precursor and application | 珠海市丝域生物科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-1999004752-A9 | METHODS FOR TREATING SKIN PIGMENTATION | JOHNSON & JOHNSON CONSUMER (US) | 1999-04-08 | — | — | WO | disclosed |
| WO-1999004752-A2 | METHODS FOR TREATING SKIN PIGMENTATION | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 1999-02-04 | — | — | WO | disclosed |
| US-5368610-A | Use of metal salts and chelates together with chlorites as oxidants in hair coloring | CLAIROL INCORPORATED (US) | 1994-11-29 | — | — | US | disclosed |
| EP-0621029-A1 | Use of metal salts and chelates together with chlorites as oxidants in hair coloring | Bristol-Myers Squibb Company (US) | 1994-10-26 | — | — | EP | disclosed |
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | disclosed |
| US-5126125-A | Decreasing the melanin content in mammalian skin and hair using 5,6-dihydroxindole derivatives | YALE UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |
| US-4956174-A | COSMETICS, TANNING, PIGMENTATION | L'OREAL (FR) | 1990-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255934-A1 | NURR1 RECEPTOR MODULATORS AND USES THEREOF | NCOR1, NCOR2, NR4A2 | CYP2A6 3418/4885TYR 4567/4885USP2 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.