Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515472 | 0.93 | CYP2A6 (0.42) | CYP2A6TYRUSP2GAAALOX15 | |
| SCHEMBL9736014 | 0.79 | TLR8 (0.49) | CYP2A6BACE1GPR84APPMAPT | |
| SCHEMBL1959555 | 0.77 | POLB (0.50) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL19506399 | 0.77 | TYR (0.46) | CYP2A6TYRUSP2GAAALOX15 | |
| SCHEMBL9735764 | 0.77 | KDM4E (0.40) | CYP2A6GAABACE1GPR84APP | |
| SCHEMBL9736443 | 0.77 | KDM4E (0.40) | CYP2A6GAABACE1GPR84APP | |
| SCHEMBL9442085 | 0.75 | BACE1 (0.42) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL8415403 | 0.75 | INPPL1 (0.42) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL31375356 | 0.73 | TYR (0.58) | CYP2A6TYRUSP2GAAALOX15 | |
| SCHEMBL28298713 | 0.73 | TYR (0.58) | CYP2A6TYRUSP2GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126125-A | Decreasing the melanin content in mammalian skin and hair using 5,6-dihydroxindole derivatives | YALE UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |
| US-4956174-A | COSMETICS, TANNING, PIGMENTATION | L'OREAL (FR) | 1990-09-11 | — | — | US | disclosed |
| US-4822375-A | LIGHTFAST, WEATHER RESISTANT, NATURAL APPEARING HAIR DYES | L'OREAL (FR) | 1989-04-18 | — | — | US | disclosed |