Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736443 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1GAATSHRRAB9A | |
| SCHEMBL1701759 | 0.89 | CA12 (0.46) | KDM4EALDH1A1GAATSHRRAB9A | |
| SCHEMBL7043680 | 0.84 | TNFSF11 (0.51) | TSHRCA12CA9TUBB4ATUBB | |
| SCHEMBL9736014 | 0.82 | TLR8 (0.49) | RAB9ACYP2A6TUBB4ATUBBTUBA3C | |
| SCHEMBL6717966 | 0.80 | TYR (0.60) | KDM4EALDH1A1GAAHPGDENPP2 | |
| SCHEMBL19186866 | 0.80 | S1PR1 (0.44) | KDM4EALDH1A1GAATSHRRAB9A | |
| SCHEMBL9442085 | 0.79 | BACE1 (0.42) | KDM4EALDH1A1GAATSHRRAB9A | |
| SCHEMBL1702125 | 0.79 | BACE1 (0.42) | KDM4EALDH1A1GAAHPGDENPP2 | |
| SCHEMBL9413340 | 0.79 | ACHE (0.47) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| SCHEMBL23417682 | 0.79 | CA12 (0.38) | KDM4EALDH1A1GAATSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126125-A | Decreasing the melanin content in mammalian skin and hair using 5,6-dihydroxindole derivatives | YALE UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |
| US-4956174-A | COSMETICS, TANNING, PIGMENTATION | L'OREAL (FR) | 1990-09-11 | — | — | US | disclosed |
| US-4822375-A | LIGHTFAST, WEATHER RESISTANT, NATURAL APPEARING HAIR DYES | L'OREAL (FR) | 1989-04-18 | — | — | US | disclosed |