Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442085 | 0.94 | BACE1 (0.42) | BACE1TYRUSP2GAAALOX15 | |
| SCHEMBL1701759 | 0.88 | CA12 (0.46) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL9511892 | 0.88 | BCHE (0.44) | BACE1GAASLC22A6MAOAKDM4E | |
| SCHEMBL8609809 | 0.84 | NPSR1 (0.41) | BACE1TYRUSP2GAAALOX15 | |
| SCHEMBL9413340 | 0.84 | ACHE (0.47) | SLC22A6MAOAKDM4EALDH1A1HPGD | |
| SCHEMBL8050935 | 0.83 | ELANE (0.40) | BACE1TYRUSP2GAAALOX15 | |
| SCHEMBL27454439 | 0.83 | CSNK2A1 (0.47) | GAASLC22A6MAOAKDM4EALDH1A1 | |
| SCHEMBL7043680 | 0.83 | TNFSF11 (0.51) | BACE1APPMAPTTUBB4ATUBB | |
| SCHEMBL6717966 | 0.82 | TYR (0.60) | BACE1TYRUSP2GAAALOX15 | |
| SCHEMBL4611118 | 0.81 | BACE1 (0.39) | BACE1TYRUSP2GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024205052-A1 | COMPOSITION FOR COLORING HAIR | 주식회사 엘지생활건강 | 2024-10-03 | — | — | WO | claimed |
| US-10292921-B2 | Hair dyeing process using a composition comprising at least one indol(in)e compound and a polycyclic aromatic compound containing at least ten carbon atoms | L'OREAL (FR) | 2019-05-21 | — | — | US | claimed |
| US-20180092822-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | L'OREAL (FR) | 2018-04-05 | — | — | US | claimed |
| EP-2582351-B1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT | L'ORÉAL (FR) | 2017-08-02 | — | — | EP | claimed |
| EP-3148648-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | L'OREAL (FR) | 2017-04-05 | — | — | EP | claimed |
| WO-2015181244-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | L'OREAL (FR) | 2015-12-03 | — | — | WO | claimed |
| EP-0971682-B2 | DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2009-09-23 | — | — | EP | claimed |
| EP-1464323-B1 | Fluorescent dye composition for human keratin fibres | OREAL (FR) | 2006-12-13 | — | — | EP | claimed |
| EP-1464323-A1 | Fluorescent dye composition for human keratin fibres | L'OREAL (FR) | 2004-10-06 | — | — | EP | claimed |
| EP-0971682-B1 | DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2004-03-17 | — | — | EP | claimed |
| EP-0462883-A1 | Keratinous fibres dyeing process with indols, compositions and devices | L'OREAL (FR) | 1991-12-27 | — | — | EP | claimed |
| US-5064442-A | HAIR DYES | L'OREAL (FR) | 1991-11-12 | — | — | US | claimed |
| EP-0446132-A1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| US-5021067-A | Rapid oxidation dyes for darkening hair; 5,6-dioxyindole derivatives | L'OREAL (FR) | 1991-06-04 | — | — | US | claimed |
| CN-1051727-A | Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-5011500-A | Developing with source of iodide ions and hydrogen peroxide, nitrite source and oxidizing agents; multicompartment kit; oxidation system; color- and washfast | L'OREAL (FR) | 1991-04-30 | — | — | US | claimed |
| EP-0415802-A1 | Keratinous fibres dyeing process with monohydroxyindole and hydroxyindole-5,6-disubstituted and composition | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |
| EP-0378937-A1 | Process for dyeing keratinous fibres with indole derivatives associated with nitrite, and compositions therefor | L'OREAL (FR) | 1990-07-25 | — | — | EP | claimed |
| US-4885006-A | Process for dyeing keratinous fibres with indole derivatives combined with an iodide | L'OREAL (FR) | 1989-12-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092822-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | KRT18, TYR, INCENP | BACE1 870/4885TYR 2/4885USP2 3709/4885 |
| US-10292921-B2 | Hair dyeing process using a composition comprising at least one indol(in)e compound and a polycyclic aromatic compound containing at least ten carbon atoms | KRT18, TYR, INCENP | BACE1 954/4885TYR 2/4885USP2 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.