Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508109 | 0.86 | ADRB2 (0.48) | FFAR1ITGB3ITGA2BCYSLTR2 | |
| SCHEMBL4522084 | 0.82 | HRH3 (0.48) | FFAR1LMNACYSLTR2 | |
| SCHEMBL4512297 | 0.80 | CYSLTR2 (0.45) | CYSLTR2 | |
| SCHEMBL3064272 | 0.79 | THRA (0.57) | FFAR1FFAR4 | |
| SCHEMBL4530820 | 0.78 | FFAR1 (0.88) | FFAR1LMNAL3MBTL1FFAR4PPARG | |
| SCHEMBL3059752 | 0.78 | THRA (0.61) | FFAR1ITGB3ITGA2BLMNAL3MBTL1 | |
| SCHEMBL1586984 | 0.78 | MEN1 (0.62) | FFAR1ITGB3ITGA2BLMNAL3MBTL1 | |
| SCHEMBL14145205 | 0.77 | CYSLTR2 (0.61) | FFAR1ITGB3ITGA2BCYSLTR2 | |
| SCHEMBL31660990 | 0.77 | HRH3 (0.44) | CYSLTR2 | |
| SCHEMBL24723561 | 0.76 | L3MBTL1 (0.82) | FFAR1LMNAL3MBTL1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740540-A1 | PHENYL ACETAMIDES | Bayer HealthCare AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103001-A1 | PHENYL ACETAMIDES | BAYER HEALTHCARE AG (DE) | 2005-11-03 | — | — | WO | disclosed |