Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595117 | 0.90 | PRKAA2 (0.60) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL27685938 | 0.90 | PRKAA2 (0.60) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| Toluene SCHEMBL27930704 | 0.87 | PRKAA2 (0.57) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL356302 | 0.84 | PRKAA2 (0.61) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL1744135 | 0.81 | PRKAA2 (0.67) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL13861857 | 0.79 | PRKAA2 (0.65) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL18791302 | 0.78 | PRKAA2 (0.61) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL13257547 | 0.77 | NR4A2 (0.65) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL6068355 | 0.76 | PRKAA2 (0.61) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL29275375 | 0.76 | PRKAA2 (0.61) | PRKAA2RXRANR1I2NR4A2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1262476-B1 | PROCESSES FOR PREPARING QUINOLINE DERIVATIVES AND INTERMEDIATES THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-6855824-B2 | Processes for preparing quinoline derivatives and intermediates thereof | KURARAY CO., LTD. (JP) | 2005-02-15 | — | — | US | disclosed |
| US-20030125355-A1 | Processes for preparing quinoline derivatives and intermedias thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-03 | — | — | US | disclosed |
| EP-1262476-A1 | PROCESSES FOR PREPARING QUINOLINE DERIVATIVES AND INTERMEDIATES THEREOF | KURARAY CO., LTD. (JP) | 2002-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125355-A1 | Processes for preparing quinoline derivatives and intermedias thereof | NQO1, ADH1B, IDH3B | PRKAA2 2107/4885RXRA 851/4885NR1I2 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.