SCHEMBL5154964

SCHEMBL5154964

CCCC(O)(CO)C(=O)OC(=O)C(O)(CO)CCC

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.34
GAA P10253 2/20 0.34
ALOX12 P18054 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.31
PKM P14618 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ELANE P08246 1/20 0.31
CYP4F2 P78329 2/20 0.31
CYP4A11 Q02928 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2306623 0.85 FDPS (0.41) FDPSGAAMEN1KMT2A
SCHEMBL12952357 0.84 ALDH1A1 (0.38) FDPSGAAALOX12CYP2C19ALDH1A1
SCHEMBL6689588 0.84 GAA (0.33) FDPSGAAALOX12CYP2C19ALDH1A1
SCHEMBL7537623 0.83 SMPD1 (0.43) FDPSMEN1KMT2A
SCHEMBL1064519 0.83 SMPD1 (0.43) FDPSMEN1KMT2A
SCHEMBL1068426 0.83 SMPD1 (0.43) FDPSMEN1KMT2A
SCHEMBL4105971 0.83 SMPD1 (0.43) FDPSMEN1KMT2A
SCHEMBL1499940 0.83 SMPD1 (0.43) FDPSMEN1KMT2A
SCHEMBL7538243 0.83 SMPD1 (0.43) FDPSMEN1KMT2A
SCHEMBL19419871 0.82 PKM (0.46) GAAALDH1A1LMNAHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0660696-B2 LIPSTICKS PROCTER & GAMBLE (US) 2007-01-10 EP disclosed
EP-1150645-B1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 PROCTER & GAMBLE (US) 2005-08-24 EP disclosed
EP-0950392-B1 Non-sweating lipsticks PROCTER & GAMBLE (US) 2004-12-29 EP disclosed
EP-1152733-B1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 PROCTER & GAMBLE (US) 2004-01-07 EP disclosed
EP-1152732-B1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 PROCTER & GAMBLE (US) 2003-11-05 EP disclosed
US-6528071-B2 Containing vitamin B3 THE PROCTER & GAMBLE COMPANY 2003-03-04 US disclosed
US-6455055-B1 COSMETIC COMPOSITIONS INCLUDING LIPSTICKS, A CRYSTALLINE VITAMIN B.SUB.3 OR NIACIN, AN EMOLLIENT COMPONENT; , OF A SOLIDIFYING AGENT. THE COMPOSITIONS PROVIDE IMPROVED SKIN FEEL OF CRYSTALLINE VITAMIN B3 FOR SKIN THE PROCTER & GAMBLE COMPANY 2002-09-24 US disclosed
WO-2002036074-A2 PIGMENTED LIQUID CRYSTAL MATERIALS PRESPERSE INCORPORATED (US) 2002-05-10 WO disclosed
US-6325995-B1 Lipsticks compositions containing association structures THE PROCTER & GAMBLE COMPANY 2001-12-04 US disclosed
EP-1152732-A1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 THE PROCTER & GAMBLE COMPANY (US) 2001-11-14 EP disclosed
WO-2000047182-A1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2000-08-17 WO disclosed
WO-2000047170-A1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B¿3? THE PROCTER & GAMBLE COMPANY (US) 2000-08-17 WO disclosed
WO-2000047169-A1 COSMETIC COMPOSITIONS CONTAINING VITAMIN B3 THE PROCTER & GAMBLE COMPANY (US) 2000-08-17 WO disclosed
EP-0950392-A1 Non-sweating lipsticks THE PROCTER & GAMBLE COMPANY (US) 1999-10-20 EP disclosed
US-5843407-A Non-sweating lipsticks THE PROCTER & GAMBLE COMPANY (US) 1998-12-01 US disclosed
EP-0660696-B1 LIPSTICKS PROCTER & GAMBLE (US) 1997-01-08 EP disclosed
EP-0725620-A1 NON-SWEATING LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1996-08-14 EP disclosed
EP-0660696-A1 LIPSTICKS. PROCTER & GAMBLE (US) 1995-07-05 EP disclosed
WO-1995011000-A1 NON-SWEATING LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1995-04-27 WO disclosed
WO-1994006400-A1 LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1994-03-31 WO disclosed