Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6269760 | 0.99 | LMNA (0.39) | LMNASMN1; SMN2HPGDMAPTMAPK1 | |
| SCHEMBL5157396 | 0.80 | MAPT (0.39) | LMNASMN1; SMN2HPGDMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6271312 | 0.79 | MAPT (0.38) | LMNASMN1; SMN2HPGDMAPTMAPK1 | |
| SCHEMBL5158086 | 0.78 | MEN1 (0.43) | SMN1; SMN2MAPTMAPK1HDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL5227051 | 0.77 | MEN1 (0.42) | LMNASMN1; SMN2MAPTMAPK1HDAC1 | |
| Hydrochloric Acid SCHEMBL7700418 | 0.76 | MEN1 (0.41) | LMNASMN1; SMN2MAPTMAPK1HDAC6 | |
| SCHEMBL7373085 | 0.73 | SHMT2 (0.49) | LMNAHPGDHDAC1HDAC3HDAC2 | |
| SCHEMBL6943172 | 0.73 | MAPT (0.49) | LMNASMN1; SMN2HPGDMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6940683 | 0.72 | HPGD (0.48) | LMNASMN1; SMN2HPGDMAPTMAPK1 | |
| SCHEMBL6945490 | 0.71 | LMNA (0.41) | LMNASMN1; SMN2HPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334713-B1 | Dyeing composition comprising diaminopyrazole and cationic compounds as oxidation bases and a coupling agent | OREAL (FR) | 2005-12-07 | — | — | EP | claimed |
| EP-1334713-A1 | Dyeing composition comprising diaminopyrazole and cationic compounds as oxidation bases and a coupling agent | L'OREAL (FR) | 2003-08-13 | — | — | EP | claimed |
| EP-0984007-A1 | Cationic orthophenylenediamines, their use for the oxidation dyeing of keratinous fibres, dyeing compositions and dyeing methods | L'OREAL (FR) | 2000-03-08 | — | — | EP | claimed |
| EP-1056435-B9 | DYEING METHOD USING AN HETEROCYCLIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | OREAL (FR) | 2007-01-10 | — | — | EP | disclosed |
| EP-1056435-B1 | DYEING METHOD USING AN HETEROCYCLIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | OREAL (FR) | 2006-06-28 | — | — | EP | disclosed |
| EP-1334713-B1 | Dyeing composition comprising diaminopyrazole and cationic compounds as oxidation bases and a coupling agent | OREAL (FR) | 2005-12-07 | — | — | EP | disclosed |
| EP-1334713-A1 | Dyeing composition comprising diaminopyrazole and cationic compounds as oxidation bases and a coupling agent | L'OREAL (FR) | 2003-08-13 | — | — | EP | disclosed |
| EP-1056435-A1 | DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | L'OREAL (FR) | 2000-12-06 | — | — | EP | disclosed |
| WO-2000038641-A1 | DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| EP-0984007-A1 | Cationic orthophenylenediamines, their use for the oxidation dyeing of keratinous fibres, dyeing compositions and dyeing methods | L'OREAL (FR) | 2000-03-08 | — | — | EP | disclosed |