Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602461 | 0.96 | CCNT1 (0.49) | SCN9ACCNT1CDK9USP2TSHR | |
| SCHEMBL5151251 | 0.96 | CCNT1 (0.49) | SCN9ACCNT1CDK9USP2TSHR | |
| SCHEMBL5151092 | 0.94 | USP2 (0.51) | SCN9ACCNT1CDK9USP2TSHR | |
| SCHEMBL4601912 | 0.86 | SCN9A (0.50) | SCN9AUSP2TSHRCNR2SMN1; SMN2 | |
| SCHEMBL5154580 | 0.85 | ICMT (0.55) | SCN9ACNR1CNR2ICMTKMT2A | |
| SCHEMBL5154481 | 0.82 | ICMT (0.62) | SCN9ACNR1CNR2ICMTCDC25A | |
| SCHEMBL5155704 | 0.82 | ICMT (0.62) | SCN9ACNR1CNR2ICMTCDC25A | |
| SCHEMBL5151102 | 0.81 | SCN9A (0.57) | SCN9ATSHRSMN1; SMN2ICMTGAA | |
| SCHEMBL5151526 | 0.80 | SCN9A (0.49) | SCN9AICMTKMT2ACDC25A | |
| SCHEMBL4613529 | 0.79 | SCN9A (0.53) | SCN9ACCNT1CDK9ICMTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078262-A1 | Thiomorpholino steroid compounds, the use thereof for the preparation of meiosis-regulating medicaments and method for the preparation thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-04-05 | — | — | US | disclosed |
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | SCN9A 3913/4885CCNT1 810/4885CDK9 3508/4885 |
| US-20070078262-A1 | Thiomorpholino steroid compounds, the use thereof for the preparation of meiosis-regulating medicaments and method for the preparation thereof | NR5A1, CYP11A1, SHBG | SCN9A 4301/4885CCNT1 1195/4885CDK9 3459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.