Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30046342 | 0.91 | LCK (0.53) | DGAT1MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30046107 | 0.78 | MAP4K4 (0.49) | DGAT1MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31579276 | 0.77 | CYP19A1 (0.48) | CYP11B2CYP11B1XDHCYP19A1 | |
| SCHEMBL30046676 | 0.77 | DGAT1 (0.62) | DGAT1MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30782543 | 0.77 | DGAT1 (0.62) | DGAT1MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2424040 | 0.77 | DGAT1 (0.62) | DGAT1MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7006231 | 0.77 | DGAT1 (0.67) | DGAT1MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6068337 | 0.76 | DGAT1 (0.61) | DGAT1MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1270834 | 0.76 | KDM4E (0.64) | DGAT1MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27310588 | 0.74 | MKNK1 (0.54) | MAP4K4CYP11B2SLC22A12MINK1TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185116-A1 | Bicyclic compounds | TANABE SEIYAKU CO., LTD. (JP) | 2007-08-09 | — | — | US | claimed |
| EP-1771418-A2 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | TANABE SEIYAKU CO., LTD. (JP) | 2007-04-11 | — | — | EP | claimed |
| WO-2005115984-A2 | LARGE CONDUCTANCE CALCIUM-ACTIVITATED K CHANNEL OPENER | TANABE SEIYAKU CO., LTD. (JP) | 2005-12-08 | — | — | WO | claimed |
| US-20070185116-A1 | Bicyclic compounds | TANABE SEIYAKU CO., LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1771418-A2 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | TANABE SEIYAKU CO., LTD. (JP) | 2007-04-11 | — | — | EP | disclosed |
| WO-2005115984-A2 | LARGE CONDUCTANCE CALCIUM-ACTIVITATED K CHANNEL OPENER | TANABE SEIYAKU CO., LTD. (JP) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185116-A1 | Bicyclic compounds | KCNN3, KCNJ1, KCNJ2 | DGAT1 4746/4885MEN1 2839/4885CYP1A2 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.