Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.67 |
| ▸ | PPARG | P37231 | 7/20 | 0.67 |
| ▸ | PPARD | Q03181 | 7/20 | 0.67 |
| ▸ | PPARA | Q07869 | 7/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | TLR2 | O60603 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | FABP4 | P15090 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.67 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764672 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11228821 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL28439052 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9455451 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9503519 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL6803390 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL7496947 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9065811 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9066363 | 1.00 | GPR84 (0.67) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL17908855 | 0.98 | GPR84 (0.64) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566494-B1 | CXCR4 RECEPTOR COMPOUNDS | ACER THERAPEUTICS INC (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20160159861-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS, INC. (US) | 2016-06-09 | — | — | US | disclosed |
| US-20160159861-A1 | APJ Receptor Compounds | ANCHOR THERAPEUTICS, INC. (US) | 2016-06-09 | — | — | US | disclosed |
| EP-3021861-A1 | APJ RECEPTOR COMPOUNDS | Anchor Therapeutics, Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| US-9155795-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9155795-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9096646-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-9096646-B2 | CXCR4 receptor compounds | ANCHOR THERAPEUTICS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| WO-2015010045-A1 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| WO-2015010045-A1 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| WO-2010053547-A2 | CXCR5 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053547-A2 | CXCR5 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053550-A2 | CXCR4 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| EP-0396429-B1 | Polyurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same | BIOMEDICAL POLYMERS INT (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-5100992-A | Chain extended with a dicarboxylic acid, block and graft polymers, medical applications, drug delivery | BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) | 1992-03-31 | — | — | US | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |
| EP-0396429-A2 | Polyurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same | BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) | 1990-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159861-A1 | APJ Receptor Compounds | APLNR, AP1G1, AP2B1 | GPR84 44/4885PPARG 213/4885PPARD 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.