Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584683 | 0.90 | ERN1 (0.61) | PRKDCALDH1A1LMNAMAPTERN1 | |
| Bromide SCHEMBL27667716 | 0.88 | ERN1 (0.59) | PRKDCALDH1A1LMNAMAPTERN1 | |
| SCHEMBL515642 | 0.86 | PRKDC (1.00) | PRKDCALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7857299 | 0.83 | PRKDC (0.57) | PRKDCALDH1A1LMNAMAPTHPGD | |
| SCHEMBL437463 | 0.81 | ALDH1A1 (0.66) | PRKDCALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7865553 | 0.80 | ALDH1A1 (0.51) | PRKDCALDH1A1LMNAMAPTHPGD | |
| Ethane SCHEMBL28205235 | 0.79 | ALDH1A1 (0.63) | PRKDCALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7832626 | 0.78 | NPC1 (0.54) | PRKDCALDH1A1MAPTHPGDERN1 | |
| SCHEMBL30575778 | 0.78 | PRKDC (0.82) | PRKDCALDH1A1LMNAMAPTHPGD | |
| SCHEMBL172939 | 0.77 | ALDH1A1 (0.71) | ALDH1A1ERN1KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920119-B | Preparation method of aporphine alkaloid | 中国药科大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-112920119-A | Preparation method of aporphine alkaloid | 中国药科大学 | 2021-06-08 | — | — | CN | disclosed |