Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010019 | 0.71 | CA12 (0.35) | ALDH1A1PKMCA12CA1CA9 | |
| SCHEMBL5156474 | 0.69 | CA12 (0.32) | ALDH1A1PKMCA12CA1CA9 | |
| SCHEMBL29876297 | 0.69 | CA12 (0.36) | ALDH1A1PKMCA12CA1CA9 | |
| SCHEMBL230240 | 0.66 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL16875688 | 0.66 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL3132415 | 0.65 | CA12 (0.34) | ALDH1A1PKMCA12CA1CA9 | |
| SCHEMBL23781544 | 0.65 | CPT2 (0.34) | ALDH1A1PKM | |
| SCHEMBL526394 | 0.64 | ALDH1A1 (0.43) | ALDH1A1PKMCA12CA1CA9 | |
| SCHEMBL6675625 | 0.63 | CA12 (0.32) | ALDH1A1PKMCA12CA1CA9 | |
| SCHEMBL657777 | 0.63 | ALDH1A1 (0.32) | ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942996-B8 | THROMBOLYTIC AGENTS WITH ANTITHROMBOTIC ACTIVITY | UNIV SOUTHERN CALIFORNIA (US) | 2007-02-21 | — | — | EP | claimed |
| EP-0942996-A1 | THROMBOLYTIC AGENTS WITH ANTITHROMBOTIC ACTIVITY | Diatide, Inc. (US) | 1999-09-22 | — | — | EP | claimed |
| WO-1998024917-A1 | THROMBOLYTIC AGENTS WITH ANTITHROMBOTIC ACTIVITY | DIATIDE, INC. (US) | 1998-06-11 | — | — | WO | claimed |
| EP-0973552-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | Marsden, John Christopher (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998018501-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | MARSDEN, JOHN, CHRISTOPHER (GB) | 1998-05-07 | — | — | WO | disclosed |