SCHEMBL5156552

SCHEMBL5156552

C=C(NC(=O)Nc1ccc(O)cc1)C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.47
THRB P10828 3/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
GAA P10253 5/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
RECQL P46063 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CASP3 P42574 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 1/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705901 0.90 SMN1; SMN2 (0.51) MAPTGAAMEN1KMT2ARECQL
SCHEMBL5705914 0.84 MAOA (0.49) MAPTTHRBMAOAMAOBGAA
SCHEMBL5705947 0.83 MAPT (0.43) MAPTGAAMEN1KMT2ACASP3
SCHEMBL5705807 0.83 ALDH1A1 (0.48) MAPTMEN1KMT2ATRPV1SMN1; SMN2
SCHEMBL5705920 0.83 ALDH1A1 (0.51) MAPTGAAMEN1KMT2ARECQL
SCHEMBL5705952 0.83 MEN1 (0.48) MAPTMEN1KMT2ARECQLSMN1; SMN2
SCHEMBL5705825 0.82 KMT2A (0.63) MEN1KMT2ACA12CA1CA2
SCHEMBL626949 0.78 MAPT (0.73) MAPTGAAMEN1KMT2ASMN1; SMN2
SCHEMBL5705862 0.77 NPC1 (0.49) MAPTGAAL3MBTL1HTTCA12
SCHEMBL5705919 0.76 TRPV1 (0.51) MAPTGAAMEN1KMT2ATRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
EP-1129845-B1 Heat mode planographic printing plate FUJI PHOTO FILM CO LTD (JP) 2007-01-17 EP disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-7087362-B2 Heat mode-compatible planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2006-08-08 US disclosed
US-20040121263-A1 Heat mode-compatible planographic printing plate FUJI PHOTO FILM CO., LTD. 2004-06-24 US disclosed
US-6692896-B2 PHOTOSENSITIVE LAYER ON HYDROPHILIC SUPPORT; RECORDING WITH INFRARED LASER FUJI PHOTO FILM CO., LTD. (JP) 2004-02-17 US disclosed
US-20010036598-A1 Heat mode-compatible planographic printing plate FUJIFILM CORPORATION (JP) 2001-11-01 US disclosed
EP-1129845-A2 Heat mode planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-09-05 EP disclosed