SCHEMBL5705807

SCHEMBL5705807

C=C(NC(=O)Nc1cccc(O)c1)C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
CYP1A2 P05177 1/20 0.48
NLRP3 Q96P20 4/20 0.46
TRPV1 Q8NER1 3/20 0.46
RAB9A P51151 3/20 0.44
MAPT P10636 3/20 0.44
MAPK1 P28482 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
PYGL P06737 1/20 0.44
NPC1 O15118 2/20 0.43
BAZ1A Q9NRL2 1/20 0.43
LMNA P02545 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705899 0.88 HPGD (0.48) ALDH1A1CYP1A2NLRP3RAB9APYGL
SCHEMBL5705891 0.86 ALDH1A1 (0.53) ALDH1A1CYP1A2NLRP3TRPV1RAB9A
SCHEMBL5156552 0.83 MAPT (0.47) ALDH1A1TRPV1RAB9AMAPTMEN1
SCHEMBL5705920 0.82 ALDH1A1 (0.51) ALDH1A1CYP1A2TRPV1RAB9AMAPT
SCHEMBL5705901 0.79 SMN1; SMN2 (0.51) ALDH1A1TRPV1RAB9AMAPTNPC1
SCHEMBL28804346 0.79 ALDH1A1 (0.53) ALDH1A1CYP1A2TRPV1RAB9AMAPT
SCHEMBL1933135 0.77 MAPK1 (0.68) ALDH1A1CYP1A2NLRP3RAB9AMAPT
SCHEMBL5705862 0.76 NPC1 (0.49) ALDH1A1RAB9AMAPTMAPK1NPC1
SCHEMBL4118207 0.75 TRPV1 (0.74) ALDH1A1TRPV1RAB9AMAPTMAPK1
SCHEMBL3252213 0.74 ALDH1A1 (0.49) ALDH1A1CYP1A2NLRP3TRPV1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116819891-A Alkali-soluble resin polymer, preparation method thereof and positive photosensitive resin composition 徐州博康信息化学品有限公司 2023-09-29 CN disclosed
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed