Toluene

Toluene

SCHEMBL5156591

C=C(C)C(=O)N=S(=O)=O.Cc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
TSHR P16473 2/20 0.41
ALOX12 P18054 1/20 0.41
ACHE P22303 1/20 0.41
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HPGD P15428 2/20 0.34
SMN1; SMN2 Q16637 5/20 0.33
MAPT P10636 2/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
AKR1C3 P42330 1/20 0.33
ELANE P08246 1/20 0.33
POLB P06746 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL7777383 0.86 TDP1 (0.33) ALDH1A1KDM4E
Toluene SCHEMBL1692174 0.78 LMNA (0.55) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL10539493 0.78 LMNA (0.55) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL10718042 0.75 ACHE (0.65) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL8599249 0.75 LMNA (0.46) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL5155809 0.74 LMNA (0.41) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL28296329 0.74 LMNA (0.50) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL28569928 0.73 LMNA (0.55) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL29226068 0.73 NQO2 (0.40) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL6619662 0.73 LMNA (0.61) LMNATSHRALOX12ACHECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179427-B1 Planographic printing original plate FUJI PHOTO FILM CO LTD (JP) 2005-10-26 EP claimed
US-6689534-B2 USING INFRARED LASER FUJI PHOTO FILM CO., LTD. (JP) 2004-02-10 US claimed
US-20020119392-A1 Using infrared laser FUJIFILM CORPORATION (JP) 2002-08-29 US claimed
EP-1179427-A2 Planographic printing original plate FUJI PHOTO FILM CO., LTD. (JP) 2002-02-13 EP claimed
EP-1129845-B1 Heat mode planographic printing plate FUJI PHOTO FILM CO LTD (JP) 2007-01-17 EP disclosed
US-7132212-B2 Including an anodized layer formed on an aluminum plate and a recording layer recordable by infrared laser exposure on the support FUJI PHOTO FILM CO., LTD. (JP) 2006-11-07 US disclosed
US-7087362-B2 Heat mode-compatible planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2006-08-08 US disclosed
EP-1147884-B1 Planographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-02-15 EP disclosed
EP-1179427-B1 Planographic printing original plate FUJI PHOTO FILM CO LTD (JP) 2005-10-26 EP disclosed
US-20040121263-A1 Heat mode-compatible planographic printing plate FUJI PHOTO FILM CO., LTD. 2004-06-24 US disclosed
US-6749984-B2 POSITIVE-TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR THAT CAN BE WRITTEN BY HEAT FROM AN INFRARED LASER, A THERMAL HEAD OR THE LIKE, AND USED FOR SO-CALLED DIRECT PLATE-MAKING FUJI PHOTO FILM CO., LTD. (JP) 2004-06-15 US disclosed
US-6716565-B2 APPLICABLE TO IMAGE-FORMING MATERIALS SUCH AS THREE-DIMENSIONAL MODELLING BY LIGHT, HOLOGRAPHY, LITHOGRAPHIC PRINTING PLATES, COLOR PROOFS, PHOTORESISTS AND COLOR FILTERS, AND INKS, PAINTS AND ADHESIVES FUJI PHOTO FILM CO., LTD. (JP) 2004-04-06 US disclosed
EP-1266753-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-12-18 EP disclosed
US-20020119392-A1 Using infrared laser FUJIFILM CORPORATION (JP) 2002-08-29 US disclosed
EP-1223467-A2 Positive image-forming material FUJI PHOTO FILM CO., LTD. (JP) 2002-07-17 EP disclosed
EP-1179427-A2 Planographic printing original plate FUJI PHOTO FILM CO., LTD. (JP) 2002-02-13 EP disclosed
US-20010039895-A1 POSITIVE-TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR THAT CAN BE WRITTEN BY HEAT FROM AN INFRARED LASER, A THERMAL HEAD OR THE LIKE, AND USED FOR SO-CALLED DIRECT PLATE-MAKING FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
US-20010036598-A1 Heat mode-compatible planographic printing plate FUJIFILM CORPORATION (JP) 2001-11-01 US disclosed
EP-1147884-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-10-24 EP disclosed
EP-1129845-A2 Heat mode planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-09-05 EP disclosed