Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31156107 | 0.87 | NOTUM (0.36) | ALDH1A1MGLLEPHX2NOTUMRXRA | |
| SCHEMBL1918950 | 0.85 | RXRA (0.47) | ALDH1A1MGLLCYP1A2CYP2C19EPHX2 | |
| SCHEMBL29784280 | 0.85 | RXRA (0.47) | ALDH1A1MGLLCYP1A2CYP2C19EPHX2 | |
| SCHEMBL10976235 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MGLLCYP1A2CYP2C19EPHX2 | |
| SCHEMBL12293763 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MGLLCYP1A2CYP2C19EPHX2 | |
| SCHEMBL4099189 | 0.83 | SLC6A2 (0.48) | ALDH1A1MGLLCYP1A2CYP2C19EPHX2 | |
| SCHEMBL24959789 | 0.81 | KMO (0.47) | EPHX2KMO | |
| SCHEMBL24956819 | 0.81 | EPHX2 (0.55) | EPHX2RXRARXRBRXRGRAB9A | |
| SCHEMBL4314290 | 0.81 | NOTUM (0.63) | ALDH1A1MGLLCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL9712610 | 0.80 | EPHX2 (0.40) | EPHX2NOTUMRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191012-B1 | Process for the preparation of fluorine containing benzaldehydes | SALTIGO GMBH (DE) | 2007-01-17 | — | — | EP | disclosed |
| US-6596906-B2 | Reacting an fluorine containing aromatic acid chloride with hydrogen in the presence of a supported palladium catalyst and a catalyst moderator to form fluorine-containing benzaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |
| US-20030125583-A1 | Process for preparing fluorine-containing benzaldehydes | BAUMANN KATHE (DE) | 2003-07-03 | — | — | US | disclosed |
| JP-2002145822-A | METHOD FOR PRODUCING FLUORINE-CONTAINING BENZALDEHYDE | BAYER AG | 2002-05-22 | — | — | JP | disclosed |
| US-20020038055-A1 | Process for preparing fluorine-containing benzaldehydes | LANXESS DEUTSCHLAND GMBH (DE) | 2002-03-28 | — | — | US | disclosed |
| EP-1191012-A1 | Process for the preparation of fluorine containing benzaldehydes | BAYER AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-0070464-B1 | SUBSTITUTED PHENYLCYCLOPROPANECARBOXYLIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1985-10-02 | — | — | EP | disclosed |
| US-4529557-A | Fluorine substitution on phenyl ring | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-16 | — | — | US | disclosed |
| EP-0070464-A1 | Substituted phenylcyclopropanecarboxylic-acid esters, process for their preparation and their use as insecticides | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125583-A1 | Process for preparing fluorine-containing benzaldehydes | FLI1, FIP1L1, AFF4 | ALDH1A1 337/4885MGLL 1577/4885CYP1A2 1185/4885 |
| US-20020038055-A1 | Process for preparing fluorine-containing benzaldehydes | FLI1, FIP1L1, AFF4 | ALDH1A1 337/4885MGLL 1577/4885CYP1A2 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.