Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157266 | 0.93 | HTT (0.40) | HTTSMPD1HDAC1HDAC2MMP1 | |
| SCHEMBL5159877 | 0.92 | MRGPRX4 (0.40) | SMPD1HDAC1HDAC2NPC1RAB9A | |
| SCHEMBL5160128 | 0.91 | TRPM8 (0.41) | MMP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5157273 | 0.88 | FFAR1 (0.37) | MEN1KMT2APPARGPPARDPPARA | |
| SCHEMBL5157793 | 0.88 | SMN1; SMN2 (0.37) | HTTSMPD1HDAC1HDAC2MMP1 | |
| SCHEMBL6229042 | 0.86 | MAPT (0.44) | SMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL6229035 | 0.86 | MAPT (0.44) | SMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL5155175 | 0.86 | HTT (0.40) | HTTSMPD1HDAC1HDAC2MMP1 | |
| SCHEMBL5159878 | 0.84 | MRGPRX4 (0.43) | SMPD1HDAC1HDAC2NPC1RAB9A | |
| SCHEMBL5157778 | 0.84 | TRPM8 (0.42) | MMP1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189873-B2 | Propargylether derivatives, a process for their preparation and their use for controlling phytopathogenic microorganisms | SYNGENTA CORP PROTECTION, INC. (US) | 2007-03-13 | — | — | US | claimed |
| EP-1549609-B1 | PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-01-24 | — | — | EP | claimed |
| US-20060167316-A1 | Propargylether derivatives, a process for their preparation and their use for controlling phytopathogenic microorganisms | SYNGENTA CROP PROTECTION, INC. | 2006-07-27 | — | — | US | claimed |
| EP-1549609-A2 | PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS | Syngenta Participations AG (CH) | 2005-07-06 | — | — | EP | claimed |
| WO-2004033413-A2 | PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-22 | — | — | WO | claimed |
| US-7189873-B2 | Propargylether derivatives, a process for their preparation and their use for controlling phytopathogenic microorganisms | SYNGENTA CORP PROTECTION, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| EP-1549609-B1 | PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-01-24 | — | — | EP | disclosed |
| US-20060167316-A1 | Propargylether derivatives, a process for their preparation and their use for controlling phytopathogenic microorganisms | SYNGENTA CROP PROTECTION, INC. | 2006-07-27 | — | — | US | disclosed |
| EP-1549609-A2 | PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS | Syngenta Participations AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033413-A2 | PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167316-A1 | Propargylether derivatives, a process for their preparation and their use for controlling phytopathogenic microorganisms | GRHPR, CBR3, CYP8B1 | HTT 2475/4885SMPD1 3637/4885HDAC1 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.