Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153902 | 0.88 | CA2 (0.53) | POLBCA2PTGS2GAAPTGS1 | |
| SCHEMBL5153996 | 0.83 | GAA (0.52) | TSHRMAPK1POLBHTTNPSR1 | |
| SCHEMBL9644980 | 0.81 | MAPK1 (0.73) | TSHRMAPK1POLBHTTNPSR1 | |
| SCHEMBL9644978 | 0.78 | TRPA1 (0.57) | POLBCA2GAA | |
| SCHEMBL9490711 | 0.77 | POLB (0.57) | TSHRMAPK1POLBHTTCA2 | |
| SCHEMBL5153447 | 0.75 | CA2 (0.56) | HTTCA2 | |
| SCHEMBL678812 | 0.75 | CA2 (0.67) | TSHRMAPK1POLBCA2PKM | |
| SCHEMBL18715600 | 0.74 | PKM (0.73) | TSHRHTTCA2PKMGAA | |
| SCHEMBL6847517 | 0.73 | COMT (0.49) | TSHRPOLBHTTNPSR1PTGS2 | |
| SCHEMBL1615615 | 0.73 | CA2 (0.55) | MAPK1POLBCA2PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245403-B1 | Thermographic recording material with improved image tone. | AGFA GEVAERT (BE) | 2007-01-03 | — | — | EP | disclosed |
| US-6774084-B2 | BLACK AND WHITE LIGHT-INSENSITIVE THERMOGRAPHIC RECORDING MEDIA COMPRISING A THERMOSENSITIVE ELEMENT HAVING ORGANIC SILVER SALT, A 1,2-DIHYDROXYBENZENE CONTAINING AN ESTER OR SULFOXIDE GROUP AND BINDER; COVERING POWER; STORAGE STABILITY | AGFA-GEVAERT (BE) | 2004-08-10 | — | — | US | disclosed |