Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433655 | 0.88 | TBXA2R (0.66) | TBXA2RNPC1MAPTMEN1KMT2A | |
| SCHEMBL7261849 | 0.77 | TBXA2R (0.77) | TBXA2RMAPTKDM4ECYP2C9CYP3A4 | |
| SCHEMBL28827564 | 0.74 | TBXA2R (0.45) | TBXA2RNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7256296 | 0.74 | NPSR1 (0.64) | NPC1RAB9ASMN1; SMN2MAPTAHR | |
| SCHEMBL19002605 | 0.71 | GAA (0.63) | RAB9AMAPTKMT2AKDM4ECYP2C9 | |
| SCHEMBL28824955 | 0.69 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTAHR | |
| SCHEMBL29898269 | 0.69 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTAHR | |
| SCHEMBL10460903 | 0.69 | TBXA2R (0.62) | TBXA2RMAPTKDM4ECYP2C9CYP3A4 | |
| SCHEMBL10460997 | 0.68 | TBXA2R (0.61) | TBXA2RMAPTKDM4ECYP2C9CYP3A4 | |
| SCHEMBL10462906 | 0.68 | TBXA2R (0.60) | TBXA2RKDM4ECYP2C9CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507524-B1 | TOPICAL USE OF DIURETICS FOR TREATING SWELLINGS | WANK RUDOLF (DE) | 2007-01-10 | — | — | EP | disclosed |
| US-20050234107-A1 | Use of diuretics for treating swellings | WANK RUDOLF | 2005-10-20 | — | — | US | disclosed |
| EP-1507524-A1 | USE OF DIURETICS FOR TREATING SWELLINGS | Wank, Rudolf (DE) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003099271-A1 | USE OF DIURETICS FOR TREATING SWELLINGS | WANK RUDOLF (DE) | 2003-12-04 | — | — | WO | disclosed |