Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5185883 | 0.84 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL5157590 | 0.77 | PRKCA (0.33) | — | |
| SCHEMBL22854400 | 0.75 | TYR (0.33) | ALDH1A1 | |
| SCHEMBL2661142 | 0.75 | — | — | |
| SCHEMBL4382484 | 0.74 | — | — | |
| SCHEMBL14048815 | 0.74 | HRH4 (0.34) | — | |
| SCHEMBL23152925 | 0.73 | MAP3K7 (0.31) | — | |
| SCHEMBL21689931 | 0.73 | GRM2 (0.42) | MEN1ALDH1A1KMT2A | |
| SCHEMBL951906 | 0.73 | GRM2 (0.42) | MEN1ALDH1A1KMT2A | |
| SCHEMBL26536211 | 0.72 | KDM4E (0.30) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472232-B1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORP (KR) | 2007-01-24 | — | — | EP | disclosed |
| EP-1472232-A4 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORP (KR) | 2006-02-01 | — | — | EP | disclosed |
| EP-1472232-A1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | Yuhan Corporation (KR) | 2004-11-03 | — | — | EP | disclosed |
| US-6706888-B2 | REACTING A 3-HALOTETRAHYDROFURAN OR TETRAHYDROPYRAN COMPOUND WITH FORMAMIDINE OR ITS SALT IN THE PRESENCE OF A BASE TO PRODUCE A 3-(1H-IMIDAZOL-4-YL)PROPANOL DERIVATIVE; EFFICIENCY; INTERMEDIATES; ANTICARCINOGENIC AGENTS; VIRICIDES; | YUHAN CORPORATION (KR) | 2004-03-16 | — | — | US | disclosed |
| US-20030153769-A1 | Processes for preparing imidazole derivatives and salts thereof | YUHAN CORPORATION | 2003-08-14 | — | — | US | disclosed |
| WO-2003066600-A1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORPORATION (KR) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153769-A1 | Processes for preparing imidazole derivatives and salts thereof | NISCH, INF2, SRI | KDM4E 3004/4885MEN1 160/4885ALDH1A1 2401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.