SCHEMBL951906

SCHEMBL951906

NC(CCc1c[nH]cn1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 3/20 0.42
ARG1 P05089 1/20 0.40
GRIK1 P39086 2/20 0.39
GRIA1 P42261 2/20 0.39
GRIA2 P42262 2/20 0.39
GRIA3 P42263 2/20 0.39
GRIA4 P48058 2/20 0.39
GRIK2 Q13002 2/20 0.39
GRIK3 Q13003 2/20 0.39
CYP3A4 P08684 1/20 0.38
SLC7A5 Q01650 1/20 0.38
GRM6 O15303 3/20 0.38
CYP1A2 P05177 2/20 0.38
ALOX15 P16050 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
GRM8 O00222 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21689931 1.00 GRM2 (0.42) GRM2ARG1GRIK1GRIA1GRIA2
SCHEMBL29805439 1.00 GRM2 (0.42) GRM2ARG1GRIK1GRIA1GRIA2
Histidine SCHEMBL949906 0.94 SLC7A5 (0.41) GRM2ARG1GRIK1GRIA1GRIA2
SCHEMBL31690297 0.87 LTA4H (0.32)
SCHEMBL23898078 0.85 MAP3K7 (0.31)
SCHEMBL20388738 0.85 MAP3K7 (0.31)
Oxalic Acid SCHEMBL1041582 0.84 GRM2 (0.33) GRM2ARG1GRIK1GRIA1GRIA2
Glutamic Acid SCHEMBL3179814 0.84 GSR (0.49) GRM2ARG1GRIK1GRIA1GRIA2
Histidine SCHEMBL388563 0.83 SLC7A5 (0.47) GRIK1GRIA1GRIA2GRIA3GRIA4
Histidine SCHEMBL8080341 0.83 SLC7A5 (0.47) GRIK1GRIA1GRIA2GRIA3GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624454-A1 NON-COVALENT DIMER CATION, AND SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF Suzhou Protonation Chain Biotechnology Co., Ltd (CN) 2025-10-01 EP disclosed
US-20250059231-A1 Protease inhibitors PROTINHI B.V. (NL) 2025-02-20 US disclosed
WO-2024133853-A1 BIS-ESTER AND AMIDE CATIONIC LIPIDS SANOFI (FR) 2024-06-27 WO disclosed
US-20110021483-A1 Platinum (IV) Complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2011-01-27 US disclosed
EP-2170913-A1 PLATINUM (IV) COMPLEXES Platco Technologies (Proprietary) Limited (ZA) 2010-04-07 EP disclosed
WO-2008155727-A1 PLATINUM (IV) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2008-12-24 WO disclosed
US-20070258899-A1 Diagnostic and therapeutic agents KARYON-CTT LTD (FI) 2007-11-08 US disclosed
WO-2007113385-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS KARYON-CTT LTD (FI) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250059231-A1 Protease inhibitors PREP, DNPEP, TMPRSS15 GRM2 4003/4885ARG1 3284/4885GRIK1 2385/4885
US-20070258899-A1 Diagnostic and therapeutic agents YBX1, MLX, TPX2 GRM2 4412/4885ARG1 989/4885GRIK1 4162/4885
US-20110021483-A1 Platinum (IV) Complexes OTC, OAT, SLC25A11 GRM2 2820/4885ARG1 2485/4885GRIK1 1849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.