Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | S1PR4 | O95977 | 1/20 | 1.00 |
| ▸ | S1PR1 | P21453 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237966 | 1.00 | MAPT (1.00) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL11709427 | 0.80 | MAPT (0.67) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL29750885 | 0.80 | MAPT (0.67) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL3391710 | 0.74 | MAPT (0.59) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL30122135 | 0.72 | MAPT (0.56) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL6093473 | 0.72 | MAPT (0.56) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL10901434 | 0.72 | MAPT (0.56) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL14344181 | 0.71 | MAPT (0.54) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL21114410 | 0.70 | MAPT (0.56) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL105454 | 0.70 | MAPT (0.56) | MAPTKDM4ENPC1S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108383782-A | The synthetic method of 4- amidoquinaldines | 北京凯恩梅格医药科技有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-108383782-A | The synthetic method of 4- amidoquinaldines | 北京凯恩梅格医药科技有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-101347623-A | Multifunctional nanodevice platform | UNIV MICHIGAN (US) | 2009-01-21 | — | — | CN | disclosed |
| EP-1206288-B1 | TARGETED FIBERLESS RADIATIVE EFFECTORS | UNIV MICHIGAN (US) | 2007-01-10 | — | — | EP | disclosed |
| CN-1471407-A | Multifunctional nano device platform | ��ִ��������ѧ���»� | 2004-01-28 | — | — | CN | disclosed |
| EP-1301211-A2 | MULTIFUNCTIONAL NANODEVICE PLATFORM | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2003-04-16 | — | — | EP | disclosed |
| US-20020165179-A1 | Multifunctional nanodevice platform | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-11-07 | — | — | US | disclosed |
| US-6471968-B1 | DENDRIMER BASED MULTIFUNCTIONAL COMPOSITIONS FOR DISEASE DIAGNOSIS AND THERAPY (E.G. CANCER DIAGNOSIS AND THERAPY); FIRST DENDRIMER IS A POLYAMIDOAMINE (PAMAM) DENDRIMER, SECOND DENDRIMER IS A POLYPROPYLAMINE (POPAM) DENDRIMER | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-10-29 | — | — | US | disclosed |
| EP-1206288-A2 | TARGETED FIBERLESS RADIATIVE EFFECTORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001087348-A2 | MULTIFUNCTIONAL NANODEVICE PLATFORM | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001008660-A2 | TARGETED FIBERLESS RADIATIVE EFFECTORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2001-02-08 | — | — | WO | disclosed |