Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.48 |
| ▸ | HTR7 | P34969 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6210660 | 0.91 | HTR1A (0.50) | HTR1AHTR7DRD2ADRA1BADRA1D | |
| SCHEMBL6234661 | 0.82 | HTR1A (0.67) | HTR1AHTR7DRD2ADRA1BHTR6 | |
| Hydrochloric Acid SCHEMBL6406987 | 0.80 | ADRA1A (0.66) | HTR1AHTR7DRD2ADRA1BADRA1D | |
| SCHEMBL6243936 | 0.78 | ADRA1B (0.54) | HTR1AHTR7DRD2ADRA1BADRA1D | |
| Hydrochloric Acid SCHEMBL6209546 | 0.77 | ADRA1B (0.56) | HTR1AHTR7DRD2ADRA1BADRA1D | |
| SCHEMBL4526501 | 0.76 | HTR1A (0.47) | HTR1AHTR7DRD2ADRA1BADRA1D | |
| SCHEMBL5801052 | 0.76 | ADRA1A (0.48) | HTR1AHTR7ADRA1BADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL4531915 | 0.75 | HTR1A (0.48) | HTR1AHTR7DRD2ADRA1BADRA1A | |
| Hydrochloric Acid SCHEMBL5802098 | 0.75 | ADRA1A (0.47) | HTR1AHTR7ADRA1BADRA1DADRA1A | |
| SCHEMBL5157991 | 0.74 | ADRA1A (0.62) | HTR1AHTR7DRD2ADRA1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746998-A1 | COMBINATION THERAPY FOR LOWER URINARY TRACT SYMPTOMS | RANBAXY LABORATORIES, LTD. (IN) | 2007-01-31 | — | — | EP | claimed |
| WO-2005092341-A1 | COMBINATION THERAPY FOR LOWER URINARY TRACT SYMPTOMS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-06 | — | — | WO | claimed |