Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20810373 | 0.86 | HDAC1 (0.52) | ALOX5CYP4F2CYP4A11HDAC1TBXAS1 | |
| SCHEMBL5155596 | 0.84 | SMPD1 (0.55) | GAAKMT2AHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL20810595 | 0.84 | ALOX5 (0.41) | ALOX5CYP4F2CYP4A11HDAC1TBXAS1 | |
| SCHEMBL20810487 | 0.84 | ALOX5 (0.46) | ALOX5CYP4F2CYP4A11HDAC1TBXAS1 | |
| SCHEMBL20810326 | 0.84 | ALOX5 (0.46) | ALOX5CYP4F2CYP4A11HDAC1TBXAS1 | |
| SCHEMBL18020999 | 0.84 | ALOX5 (0.46) | ALOX5CYP4F2CYP4A11HDAC1TBXAS1 | |
| SCHEMBL20810288 | 0.82 | ALOX5 (0.47) | ALOX5CYP4F2CYP4A11HDAC1LMNA | |
| SCHEMBL17049469 | 0.82 | CYP4F2 (0.43) | KMT2AALOX5CYP4F2CYP4A11ATM | |
| SCHEMBL20810303 | 0.82 | MAPK1 (0.47) | GAAALOX5CYP4F2CYP4A11HDAC1 | |
| SCHEMBL16800026 | 0.82 | GPR132 (0.45) | KMT2AALOX5CYP4F2CYP4A11HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745011-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL Biomedica plc (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080316-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL BIOMEDICA PLC. (GB) | 2005-09-01 | — | — | WO | disclosed |