Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.55 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.46 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.45 |
| ▸ | LPL | P06858 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157774 | 0.86 | KMT2A (0.48) | SMPD1SPHK2SPHK1GAAKMT2A | |
| SCHEMBL20810289 | 0.85 | SPHK2 (0.59) | SMPD1SPHK2SPHK1SMN1; SMN2MAP1LC3B | |
| SCHEMBL5157983 | 0.84 | GAA (0.46) | SMPD1SPHK2SPHK1GAAKMT2A | |
| SCHEMBL20810312 | 0.82 | PPARA (0.56) | SMPD1SPHK2SPHK1SMN1; SMN2MAP1LC3B | |
| SCHEMBL29013699 | 0.81 | SMPD1 (0.67) | SMPD1SPHK2SPHK1SMN1; SMN2MAP1LC3B | |
| SCHEMBL15173985 | 0.81 | SPHK2 (0.64) | SMPD1SPHK2SPHK1SMN1; SMN2MAP1LC3B | |
| SCHEMBL15174533 | 0.81 | SPHK2 (0.64) | SMPD1SPHK2SPHK1SMN1; SMN2MAP1LC3B | |
| SCHEMBL9717443 | 0.80 | GAA (0.77) | SMPD1GAAKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL1880076 | 0.80 | SPHK2 (0.52) | SMPD1SPHK2SPHK1MAP1LC3BMAP1LC3A | |
| SCHEMBL1880075 | 0.80 | SPHK2 (0.52) | SMPD1SPHK2SPHK1MAP1LC3BMAP1LC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745011-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL Biomedica plc (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080316-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL BIOMEDICA PLC. (GB) | 2005-09-01 | — | — | WO | disclosed |