Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 2/20 | 0.34 |
| ▸ | NMT1 | P30419 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155332 | 0.94 | CYSLTR2 (0.45) | CYSLTR2TDP1KCNH2HRH3HRH2 | |
| SCHEMBL5173022 | 0.92 | NMT2 (0.39) | CYSLTR2TDP1KCNH2HRH3ALDH1A1 | |
| SCHEMBL5111128 | 0.91 | CYSLTR2 (0.47) | CYSLTR2TDP1HRH3ALDH1A1MEN1 | |
| SCHEMBL5174823 | 0.89 | CYSLTR2 (0.43) | CYSLTR2TDP1KCNH2HRH3ALDH1A1 | |
| SCHEMBL5118730 | 0.88 | CYSLTR2 (0.48) | CYSLTR2TDP1KCNH2HRH3ALDH1A1 | |
| SCHEMBL5186666 | 0.86 | YAP1 (0.39) | TDP1HRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL5113803 | 0.85 | POLB (0.48) | CYSLTR2ALDH1A1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL5125642 | 0.84 | CYSLTR2 (0.52) | CYSLTR2KCNH2HRH3 | |
| SCHEMBL5126529 | 0.82 | CYSLTR2 (0.47) | CYSLTR2TDP1KCNH2HRH3ALDH1A1 | |
| SCHEMBL5115310 | 0.81 | ALDH1A1 (0.44) | KCNH2HRH3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740540-A1 | PHENYL ACETAMIDES | Bayer HealthCare AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103001-A1 | PHENYL ACETAMIDES | BAYER HEALTHCARE AG (DE) | 2005-11-03 | — | — | WO | disclosed |